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Anti-H3F3A monoclonal antibody
Pre-made anti-H3F3A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to H3F3A/H3F3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T90766-Ab-1/ GM-Tg-hg-T90766-Ab-2 | Anti-Human H3F3A monoclonal antibody | Human |
| GM-Tg-rg-T90766-Ab-1/ GM-Tg-rg-T90766-Ab-2 | Anti-Rat H3F3A monoclonal antibody | Rat |
| GM-Tg-mg-T90766-Ab-1/ GM-Tg-mg-T90766-Ab-2 | Anti-Mouse H3F3A monoclonal antibody | Mouse |
| GM-Tg-cynog-T90766-Ab-1/ GM-Tg-cynog-T90766-Ab-2 | Anti-Cynomolgus/ Rhesus macaque H3F3A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T90766-Ab-1/ GM-Tg-felg-T90766-Ab-2 | Anti-Feline H3F3A monoclonal antibody | Feline |
| GM-Tg-cang-T90766-Ab-1/ GM-Tg-cang-T90766-Ab-2 | Anti-Canine H3F3A monoclonal antibody | Canine |
| GM-Tg-bovg-T90766-Ab-1/ GM-Tg-bovg-T90766-Ab-2 | Anti-Bovine H3F3A monoclonal antibody | Bovine |
| GM-Tg-equg-T90766-Ab-1/ GM-Tg-equg-T90766-Ab-2 | Anti-Equine H3F3A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T90766-Ab-1/ GM-Tg-hg-T90766-Ab-2; GM-Tg-rg-T90766-Ab-1/ GM-Tg-rg-T90766-Ab-2; GM-Tg-mg-T90766-Ab-1/ GM-Tg-mg-T90766-Ab-2; GM-Tg-cynog-T90766-Ab-1/ GM-Tg-cynog-T90766-Ab-2; GM-Tg-felg-T90766-Ab-1/ GM-Tg-felg-T90766-Ab-2; GM-Tg-cang-T90766-Ab-1/ GM-Tg-cang-T90766-Ab-2; GM-Tg-bovg-T90766-Ab-1/ GM-Tg-bovg-T90766-Ab-2; GM-Tg-equg-T90766-Ab-1/ GM-Tg-equg-T90766-Ab-2 |
| Products Name | Anti-H3F3A monoclonal antibody |
| Format | mab |
| Target Name | H3F3A |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-H3F3A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T90766-Ag-1 | Recombinant multi-species H33/ H3F3A/ H3.3A protein |
| ORF Viral Vector | pGMLP004571 | human H3F3A Lentivirus plasmid |
| ORF Viral Vector | vGMLP004571 | human H3F3A Lentivirus particle |
Target information
| Target ID | GM-T90766 |
| Target Name | H3F3A |
| Gene ID | 3020,15078,100361558,699443,480110,100169960,326601,100054462 |
| Gene Symbol and Synonyms | BRYLIB1,EyeLinc14,H3-3A,H3-3B,H3.3A,H3F3,H3F3A,H3F3B |
| Uniprot Accession | P84243,Q5E9F8 |
| Uniprot Entry Name | H33_HUMAN,H33_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000163041 |
| Target Classification | N/A |
The target: H3F3A, gene name: H3F3A, also named as H3.3A, H3F3. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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