Anti-S15A1/ SLC15A1/ HPECT1 monoclonal antibody

Anti-S15A1/ SLC15A1/ HPECT1 antibody for FACS & in-vivo assay

Target products collectionGo to SLC15A1/SLC15A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T91180-Ab-1/ GM-Tg-hg-T91180-Ab-2Anti-Human SLC15A1 monoclonal antibodyHuman
GM-Tg-rg-T91180-Ab-1/ GM-Tg-rg-T91180-Ab-2Anti-Rat SLC15A1 monoclonal antibodyRat
GM-Tg-mg-T91180-Ab-1/ GM-Tg-mg-T91180-Ab-2Anti-Mouse SLC15A1 monoclonal antibodyMouse
GM-Tg-cynog-T91180-Ab-1/ GM-Tg-cynog-T91180-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC15A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T91180-Ab-1/ GM-Tg-felg-T91180-Ab-2Anti-Feline SLC15A1 monoclonal antibodyFeline
GM-Tg-cang-T91180-Ab-1/ GM-Tg-cang-T91180-Ab-2Anti-Canine SLC15A1 monoclonal antibodyCanine
GM-Tg-bovg-T91180-Ab-1/ GM-Tg-bovg-T91180-Ab-2Anti-Bovine SLC15A1 monoclonal antibodyBovine
GM-Tg-equg-T91180-Ab-1/ GM-Tg-equg-T91180-Ab-2Anti-Equine SLC15A1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T91180-Ab-1/ GM-Tg-hg-T91180-Ab-2; GM-Tg-rg-T91180-Ab-1/ GM-Tg-rg-T91180-Ab-2;
GM-Tg-mg-T91180-Ab-1/ GM-Tg-mg-T91180-Ab-2; GM-Tg-cynog-T91180-Ab-1/ GM-Tg-cynog-T91180-Ab-2;
GM-Tg-felg-T91180-Ab-1/ GM-Tg-felg-T91180-Ab-2; GM-Tg-cang-T91180-Ab-1/ GM-Tg-cang-T91180-Ab-2;
GM-Tg-bovg-T91180-Ab-1/ GM-Tg-bovg-T91180-Ab-2; GM-Tg-equg-T91180-Ab-1/ GM-Tg-equg-T91180-Ab-2
Products NameAnti-SLC15A1 monoclonal antibody
Formatmab
Target NameSLC15A1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC15A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species S15A1/ SLC15A1/ HPECT1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP003964human SLC15A1 Lentivirus particle
    ORF Viral VectorpGMLP003964human SLC15A1 Lentivirus plasmid
    ORF Viral VectorpGMLV000225human SLC15A1 Lentivirus plasmid
    ORF Viral VectorvGMLV000225human SLC15A1 Lentivirus particle


    Target information

    Target IDGM-T91180
    Target NameSLC15A1
    Gene ID6564,56643,117261,574257,403561,101100174,521181,100060961
    Gene Symbol and SynonymsD630032F02,HPECT1,HPEPT1,PECT1,PEPT-1,PEPT1,SLC15A1
    Uniprot AccessionP46059,P51574,Q8WMX5
    Uniprot Entry NameS15A1_HUMAN,S15A1_RAT,S15A1_CANLF
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000088386
    Target ClassificationN/A

    The target: SLC15A1, gene name: SLC15A1, also named as HPECT1, HPEPT1, PEPT1. This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs. [provided by RefSeq, Apr 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.