Anti-AOX1 monoclonal antibody

Pre-made anti-AOX1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to AOX1/AOX1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T94444-Ab-1/ GM-Tg-hg-T94444-Ab-2Anti-Human AOX1 monoclonal antibodyHuman
GM-Tg-rg-T94444-Ab-1/ GM-Tg-rg-T94444-Ab-2Anti-Rat AOX1 monoclonal antibodyRat
GM-Tg-mg-T94444-Ab-1/ GM-Tg-mg-T94444-Ab-2Anti-Mouse AOX1 monoclonal antibodyMouse
GM-Tg-cynog-T94444-Ab-1/ GM-Tg-cynog-T94444-Ab-2Anti-Cynomolgus/ Rhesus macaque AOX1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T94444-Ab-1/ GM-Tg-felg-T94444-Ab-2Anti-Feline AOX1 monoclonal antibodyFeline
GM-Tg-cang-T94444-Ab-1/ GM-Tg-cang-T94444-Ab-2Anti-Canine AOX1 monoclonal antibodyCanine
GM-Tg-bovg-T94444-Ab-1/ GM-Tg-bovg-T94444-Ab-2Anti-Bovine AOX1 monoclonal antibodyBovine
GM-Tg-equg-T94444-Ab-1/ GM-Tg-equg-T94444-Ab-2Anti-Equine AOX1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T94444-Ab-1/ GM-Tg-hg-T94444-Ab-2; GM-Tg-rg-T94444-Ab-1/ GM-Tg-rg-T94444-Ab-2;
GM-Tg-mg-T94444-Ab-1/ GM-Tg-mg-T94444-Ab-2; GM-Tg-cynog-T94444-Ab-1/ GM-Tg-cynog-T94444-Ab-2;
GM-Tg-felg-T94444-Ab-1/ GM-Tg-felg-T94444-Ab-2; GM-Tg-cang-T94444-Ab-1/ GM-Tg-cang-T94444-Ab-2;
GM-Tg-bovg-T94444-Ab-1/ GM-Tg-bovg-T94444-Ab-2; GM-Tg-equg-T94444-Ab-1/ GM-Tg-equg-T94444-Ab-2
Products NameAnti-AOX1 monoclonal antibody
Formatmab
Target NameAOX1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-AOX1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T94444-Ag-1Recombinant multi-species AOXA/ AOX1/ AO protein


    Target information

    Target IDGM-T94444
    Target NameAOX1
    Gene ID316,11761,54349,701024,101085487,338074
    Gene Symbol and SynonymsAO,AOH1,Aox-1,Aox-2,AOX1,Aox2,Moro,Ro
    Uniprot AccessionQ06278,Q9Z0U5,P48034
    Uniprot Entry NameAOXA_HUMAN,AOXA_RAT,AOXA_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000138356
    Target ClassificationN/A

    The target: AOX1, gene name: AOX1, also named as AO, AOH1. Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.