- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-TR13B/ TNFRSF13B/ CD267 monoclonal antibody
Anti-TR13B/ TNFRSF13B/ CD267 antibody for FACS & in-vivo assay
Go to TNFRSF13B/TNFRSF13B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T99394-Ab-1/ GM-Tg-hg-T99394-Ab-2 | Anti-Human TNFRSF13B monoclonal antibody | Human |
| GM-Tg-rg-T99394-Ab-1/ GM-Tg-rg-T99394-Ab-2 | Anti-Rat TNFRSF13B monoclonal antibody | Rat |
| GM-Tg-mg-T99394-Ab-1/ GM-Tg-mg-T99394-Ab-2 | Anti-Mouse TNFRSF13B monoclonal antibody | Mouse |
| GM-Tg-cynog-T99394-Ab-1/ GM-Tg-cynog-T99394-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TNFRSF13B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T99394-Ab-1/ GM-Tg-felg-T99394-Ab-2 | Anti-Feline TNFRSF13B monoclonal antibody | Feline |
| GM-Tg-cang-T99394-Ab-1/ GM-Tg-cang-T99394-Ab-2 | Anti-Canine TNFRSF13B monoclonal antibody | Canine |
| GM-Tg-bovg-T99394-Ab-1/ GM-Tg-bovg-T99394-Ab-2 | Anti-Bovine TNFRSF13B monoclonal antibody | Bovine |
| GM-Tg-equg-T99394-Ab-1/ GM-Tg-equg-T99394-Ab-2 | Anti-Equine TNFRSF13B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T99394-Ab-1/ GM-Tg-hg-T99394-Ab-2; GM-Tg-rg-T99394-Ab-1/ GM-Tg-rg-T99394-Ab-2; GM-Tg-mg-T99394-Ab-1/ GM-Tg-mg-T99394-Ab-2; GM-Tg-cynog-T99394-Ab-1/ GM-Tg-cynog-T99394-Ab-2; GM-Tg-felg-T99394-Ab-1/ GM-Tg-felg-T99394-Ab-2; GM-Tg-cang-T99394-Ab-1/ GM-Tg-cang-T99394-Ab-2; GM-Tg-bovg-T99394-Ab-1/ GM-Tg-bovg-T99394-Ab-2; GM-Tg-equg-T99394-Ab-1/ GM-Tg-equg-T99394-Ab-2 |
| Products Name | Anti-TNFRSF13B monoclonal antibody |
| Format | mab |
| Target Name | TNFRSF13B |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TNFRSF13B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species TR13B/ TNFRSF13B/ CD267 VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-T99394-Ag-1 | tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) protein |
Target information
| Target ID | GM-T99394 |
| Target Name | TNFRSF13B |
| Gene ID | 23495,57916,103693341,574200,609580,101089305,617948,100051166 |
| Gene Symbol and Synonyms | 1200009E08Rik,CD267,CVID,CVID2,IGAD2,NF-AT,RYZN,TACI,TNFRSF13B,TNFRSF14B |
| Uniprot Accession | O14836 |
| Uniprot Entry Name | TR13B_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target, Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000240505 |
| Target Classification | Checkpoint-Immuno Oncology |
The target: TNFRSF13B, gene name: TNFRSF13B, also named as CD267, CVID, CVID2, IGAD2, RYZN, TACI, TNFRSF14B. The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
