- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-CSNK1E monoclonal antibody
Pre-made anti-CSNK1E monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to CSNK1E/CSNK1E products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T99989-Ab-1/ GM-Tg-hg-T99989-Ab-2 | Anti-Human CSNK1E monoclonal antibody | Human |
| GM-Tg-rg-T99989-Ab-1/ GM-Tg-rg-T99989-Ab-2 | Anti-Rat CSNK1E monoclonal antibody | Rat |
| GM-Tg-mg-T99989-Ab-1/ GM-Tg-mg-T99989-Ab-2 | Anti-Mouse CSNK1E monoclonal antibody | Mouse |
| GM-Tg-cynog-T99989-Ab-1/ GM-Tg-cynog-T99989-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CSNK1E monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T99989-Ab-1/ GM-Tg-felg-T99989-Ab-2 | Anti-Feline CSNK1E monoclonal antibody | Feline |
| GM-Tg-cang-T99989-Ab-1/ GM-Tg-cang-T99989-Ab-2 | Anti-Canine CSNK1E monoclonal antibody | Canine |
| GM-Tg-bovg-T99989-Ab-1/ GM-Tg-bovg-T99989-Ab-2 | Anti-Bovine CSNK1E monoclonal antibody | Bovine |
| GM-Tg-equg-T99989-Ab-1/ GM-Tg-equg-T99989-Ab-2 | Anti-Equine CSNK1E monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T99989-Ab-1/ GM-Tg-hg-T99989-Ab-2; GM-Tg-rg-T99989-Ab-1/ GM-Tg-rg-T99989-Ab-2; GM-Tg-mg-T99989-Ab-1/ GM-Tg-mg-T99989-Ab-2; GM-Tg-cynog-T99989-Ab-1/ GM-Tg-cynog-T99989-Ab-2; GM-Tg-felg-T99989-Ab-1/ GM-Tg-felg-T99989-Ab-2; GM-Tg-cang-T99989-Ab-1/ GM-Tg-cang-T99989-Ab-2; GM-Tg-bovg-T99989-Ab-1/ GM-Tg-bovg-T99989-Ab-2; GM-Tg-equg-T99989-Ab-1/ GM-Tg-equg-T99989-Ab-2 |
| Products Name | Anti-CSNK1E monoclonal antibody |
| Format | mab |
| Target Name | CSNK1E |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-CSNK1E monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T99989-Ag-1 | Recombinant multi-species KC1E/ CSNK1E/ CKIe protein |
| ORF Viral Vector | pGMAP000186 | Human CSNK1E Adenovirus plasmid |
| ORF Viral Vector | vGMLP002478 | human CSNK1E Lentivirus particle |
| ORF Viral Vector | pGMLP002478 | human CSNK1E Lentivirus plasmid |
| ORF Viral Vector | vGMAP000186 | Human CSNK1E Adenovirus particle |
| ORF Viral Vector | pGMLPm002633 | mouse Csnk1e Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002633 | mouse Csnk1e Lentivirus particle |
Target information
| Target ID | GM-T99989 |
| Target Name | CSNK1E |
| Gene ID | 1454,27373 |
| Gene Symbol and Synonyms | CK1epsilon,CKIe,CKIepsilon,CSNK1E,HCKIE,KC1epsilon,tau |
| Uniprot Accession | P49674 |
| Uniprot Entry Name | KC1E_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000213923 |
| Target Classification | Kinase |
The target: CSNK1E, gene name: CSNK1E, also named as CKIe, CKIepsilon, HCKIE. The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
