Anti-EEF1A2 monoclonal antibody
Pre-made anti-EEF1A2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-TA126-Ab-1/ GM-Tg-hg-TA126-Ab-2 | Anti-Human EEF1A2 monoclonal antibody | Human |
GM-Tg-rg-TA126-Ab-1/ GM-Tg-rg-TA126-Ab-2 | Anti-Rat EEF1A2 monoclonal antibody | Rat |
GM-Tg-mg-TA126-Ab-1/ GM-Tg-mg-TA126-Ab-2 | Anti-Mouse EEF1A2 monoclonal antibody | Mouse |
GM-Tg-cynog-TA126-Ab-1/ GM-Tg-cynog-TA126-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EEF1A2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-TA126-Ab-1/ GM-Tg-felg-TA126-Ab-2 | Anti-Feline EEF1A2 monoclonal antibody | Feline |
GM-Tg-cang-TA126-Ab-1/ GM-Tg-cang-TA126-Ab-2 | Anti-Canine EEF1A2 monoclonal antibody | Canine |
GM-Tg-bovg-TA126-Ab-1/ GM-Tg-bovg-TA126-Ab-2 | Anti-Bovine EEF1A2 monoclonal antibody | Bovine |
GM-Tg-equg-TA126-Ab-1/ GM-Tg-equg-TA126-Ab-2 | Anti-Equine EEF1A2 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-TA126-Ab-1/ GM-Tg-hg-TA126-Ab-2; GM-Tg-rg-TA126-Ab-1/ GM-Tg-rg-TA126-Ab-2; GM-Tg-mg-TA126-Ab-1/ GM-Tg-mg-TA126-Ab-2; GM-Tg-cynog-TA126-Ab-1/ GM-Tg-cynog-TA126-Ab-2; GM-Tg-felg-TA126-Ab-1/ GM-Tg-felg-TA126-Ab-2; GM-Tg-cang-TA126-Ab-1/ GM-Tg-cang-TA126-Ab-2; GM-Tg-bovg-TA126-Ab-1/ GM-Tg-bovg-TA126-Ab-2; GM-Tg-equg-TA126-Ab-1/ GM-Tg-equg-TA126-Ab-2 |
Products Name | Anti-EEF1A2 monoclonal antibody |
Format | mab |
Target Name | EEF1A2 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-EEF1A2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-TA126-Ag-1 | Recombinant multi-species EF1A2/ EEF1A2/ EEF1AL protein |
ORF Viral Vector | vGMLP002670 | human EEF1A2 Lentivirus particle |
ORF Viral Vector | vGMAD000134 | human EEF1A2 Adenovirus particle |
ORF Viral Vector | pGMAD000134 | human EEF1A2 Adenovirus plasmid |
ORF Viral Vector | pGMLP002670 | human EEF1A2 Lentivirus plasmid |
ORF Viral Vector | pGMAAV000037 | mouse Eef1a2 AAV plasmid |
ORF Viral Vector | vGMAAV000037 | mouse Eef1a2 AAV particle |
Target information
Target ID | GM-TA126 |
Target Name | EEF1A2 |
Gene ID | 1917,13628,24799,696946,612521,101100798,515233,100060464 |
Gene Symbol and Synonyms | DEE33,Eef1a,EEF1A2,EEF1AL,EF-1-alpha-2,EF1A,EIEE33,HS1,MRD38,Ps10,RATPS10,S1,STN,STNL,wasted,wst |
Uniprot Accession | Q05639,P62632,Q32PH8 |
Uniprot Entry Name | EF1A2_HUMAN,EF1A2_RAT,EF1A2_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target, Immuno-oncology Target |
Disease | Cancer |
Gene Ensembl | ENSG00000101210 |
Target Classification | Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA) |
The target: EEF1A2, gene name: EEF1A2, also named as EEF1AL, EF-1-alpha-2, EF1A, EIEE33, HS1, MRD38, STN, STNL. This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. [provided by RefSeq, Mar 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.