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Anti-GADD45G monoclonal antibody
Pre-made anti-GADD45G monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to GADD45G/GADD45G products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-TA138-Ab-1/ GM-Tg-hg-TA138-Ab-2 | Anti-Human GADD45G monoclonal antibody | Human |
| GM-Tg-rg-TA138-Ab-1/ GM-Tg-rg-TA138-Ab-2 | Anti-Rat GADD45G monoclonal antibody | Rat |
| GM-Tg-mg-TA138-Ab-1/ GM-Tg-mg-TA138-Ab-2 | Anti-Mouse GADD45G monoclonal antibody | Mouse |
| GM-Tg-cynog-TA138-Ab-1/ GM-Tg-cynog-TA138-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GADD45G monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-TA138-Ab-1/ GM-Tg-felg-TA138-Ab-2 | Anti-Feline GADD45G monoclonal antibody | Feline |
| GM-Tg-cang-TA138-Ab-1/ GM-Tg-cang-TA138-Ab-2 | Anti-Canine GADD45G monoclonal antibody | Canine |
| GM-Tg-bovg-TA138-Ab-1/ GM-Tg-bovg-TA138-Ab-2 | Anti-Bovine GADD45G monoclonal antibody | Bovine |
| GM-Tg-equg-TA138-Ab-1/ GM-Tg-equg-TA138-Ab-2 | Anti-Equine GADD45G monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-TA138-Ab-1/ GM-Tg-hg-TA138-Ab-2; GM-Tg-rg-TA138-Ab-1/ GM-Tg-rg-TA138-Ab-2; GM-Tg-mg-TA138-Ab-1/ GM-Tg-mg-TA138-Ab-2; GM-Tg-cynog-TA138-Ab-1/ GM-Tg-cynog-TA138-Ab-2; GM-Tg-felg-TA138-Ab-1/ GM-Tg-felg-TA138-Ab-2; GM-Tg-cang-TA138-Ab-1/ GM-Tg-cang-TA138-Ab-2; GM-Tg-bovg-TA138-Ab-1/ GM-Tg-bovg-TA138-Ab-2; GM-Tg-equg-TA138-Ab-1/ GM-Tg-equg-TA138-Ab-2 |
| Products Name | Anti-GADD45G monoclonal antibody |
| Format | mab |
| Target Name | GADD45G |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-GADD45G monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-TA138-Ag-1 | Recombinant multi-species GA45G/ GADD45G/ CR6 protein |
| ORF Viral Vector | vGMAP000097 | Human GADD45G Adenovirus particle |
| ORF Viral Vector | pGMLP000504 | human GADD45G Lentivirus plasmid |
| ORF Viral Vector | pGMLV000185 | human GADD45G Lentivirus plasmid |
| ORF Viral Vector | vGMLP000504 | human GADD45G Lentivirus particle |
| ORF Viral Vector | pGMAP000097 | Human GADD45G Adenovirus plasmid |
| ORF Viral Vector | pGMLV000519 | human GADD45G Lentivirus plasmid |
| ORF Viral Vector | vGMLV000185 | human GADD45G Lentivirus particle |
| ORF Viral Vector | vGMLV000519 | human GADD45G Lentivirus particle |
| ORF Viral Vector | pGMLPm000711 | mouse Gadd45g Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000711 | mouse Gadd45g Lentivirus particle |
Target information
| Target ID | GM-TA138 |
| Target Name | GADD45G |
| Gene ID | 10912,23882,291005,697835,484198,101086509,504939,100054996 |
| Gene Symbol and Synonyms | CR6,DDIT2,GADD45G,GADD45gamma,GRP17,OIG37 |
| Uniprot Accession | O95257,Q9WTQ7,Q2KIX1 |
| Uniprot Entry Name | GA45G_HUMAN,GA45G_RAT,GA45G_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000130222 |
| Target Classification | N/A |
The target: GADD45G, gene name: GADD45G, also named as CR6, DDIT2, GADD45gamma, GRP17. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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