Anti-I17RE/ IL17RE monoclonal antibody

Anti-I17RE/ IL17RE antibody for FACS & in-vivo assay

Target products collectionGo to IL17RE/IL17RE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-TA182-Ab-1/ GM-Tg-hg-TA182-Ab-2Anti-Human IL17RE monoclonal antibodyHuman
GM-Tg-rg-TA182-Ab-1/ GM-Tg-rg-TA182-Ab-2Anti-Rat IL17RE monoclonal antibodyRat
GM-Tg-mg-TA182-Ab-1/ GM-Tg-mg-TA182-Ab-2Anti-Mouse IL17RE monoclonal antibodyMouse
GM-Tg-cynog-TA182-Ab-1/ GM-Tg-cynog-TA182-Ab-2Anti-Cynomolgus/ Rhesus macaque IL17RE monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-TA182-Ab-1/ GM-Tg-felg-TA182-Ab-2Anti-Feline IL17RE monoclonal antibodyFeline
GM-Tg-cang-TA182-Ab-1/ GM-Tg-cang-TA182-Ab-2Anti-Canine IL17RE monoclonal antibodyCanine
GM-Tg-bovg-TA182-Ab-1/ GM-Tg-bovg-TA182-Ab-2Anti-Bovine IL17RE monoclonal antibodyBovine
GM-Tg-equg-TA182-Ab-1/ GM-Tg-equg-TA182-Ab-2Anti-Equine IL17RE monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-TA182-Ab-1/ GM-Tg-hg-TA182-Ab-2; GM-Tg-rg-TA182-Ab-1/ GM-Tg-rg-TA182-Ab-2;
GM-Tg-mg-TA182-Ab-1/ GM-Tg-mg-TA182-Ab-2; GM-Tg-cynog-TA182-Ab-1/ GM-Tg-cynog-TA182-Ab-2;
GM-Tg-felg-TA182-Ab-1/ GM-Tg-felg-TA182-Ab-2; GM-Tg-cang-TA182-Ab-1/ GM-Tg-cang-TA182-Ab-2;
GM-Tg-bovg-TA182-Ab-1/ GM-Tg-bovg-TA182-Ab-2; GM-Tg-equg-TA182-Ab-1/ GM-Tg-equg-TA182-Ab-2
Products NameAnti-IL17RE monoclonal antibody
Formatmab
Target NameIL17RE
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IL17RE benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species I17RE/ IL17RE VLP (virus-like particle) (Products Developing)
    CytokineGM-Tg-g-TA182-Ag-1interleukin 17 receptor E (IL17RE) protein


    Target information

    Target IDGM-TA182
    Target NameIL17RE
    Gene ID132014,57890,362417,698972,484661,101091853,783335,100052054
    Gene Symbol and SynonymsIL-17RE,IL17RE,Il25r
    Uniprot AccessionQ8NFR9,Q6AZ51
    Uniprot Entry NameI17RE_HUMAN,I17RE_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, Cytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000163701
    Target ClassificationN/A

    The target: IL17RE, gene name: IL17RE, also named as . This gene encodes a transmembrane protein that functions as the receptor for interleukin-17C. The encoded protein signals to downstream components of the mitogen activated protein kinase (MAPK) pathway. Activity of this protein is important in the immune response to bacterial pathogens. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.