What is Beta-2 microglobulin (B2M) test?
Beta-2 microglobulin (B2M) is a protein that is found on the surface of nucleated cells (contain a nucleus) and functions as part of the human immune system. This protein is routinely shed by cells into the blood and is present in most body fluids, with highest levels in the blood, generally lower levels in spinal fluid, and trace levels in urine.
In the kidneys, B2M passes through blood-filtering units called the glomeruli and is then reabsorbed by the renal proximal tubules, structures that reclaim water, proteins, vitamins, minerals, and other vital substances. Normally, only small amounts of B2M are present in the urine, but when the renal tubules become damaged or diseased, B2M concentrations increase due to the decreased ability to reabsorb this protein. When the glomeruli in the kidneys are damaged, they are unable to filter out B2M, so the level in the blood rises.
Genemedi produces core diagnostic ingredients for test of kidney function (renal damages) and related syndrome.
GeneMedi offers paired diagnostics grade Beta-2 microglobulin (B2M) ) antibodies (monoclonal antibody, mab) and Beta-2 microglobulin (B2M) ) antigens for kidney function (renal damages) rapid test kit of Beta-2 microglobulin (B2M) ) testing in ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
All the antibodies and antigens for kidney function (renal damages) test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody.The antigens can be used for antibodies rapid test of kidney function (renal damages).
Order information
Description
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Cat No.
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GMP-B2M-Ag |
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Product Name
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Recombinant Beta-2 microglobulin (B2M, His Tag)
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|
Expression platform
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E.coli
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| Isotypes | Recombinant Antigen
|
| Bioactivity validation | Beta-2 microglobulin (B2M) Antibody Binding,
Immunogen in Sandwich ELISA test, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
|
| Tag | His
|
| Products description | Recombinant Beta-2 microglobulin (B2M, His Tag) is produced by E.coli expression system with a 6His tag.
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| Specics | NA
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| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | positive control,
ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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Cat No.
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GMP-B2M-Ab-1; GMP-B2M-Ab-2 |
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Product Name
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Anti-Beta-2 microglobulin (B2M) mouse monoclonal antibody(mAb)
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Expression platform
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CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Human Beta-2 microglobulin (B2M) protein binding,
ELISA validated as capture antibody and detection antibody.
Pair in B2M level test and kidney function (renal damages) evaluation.
|
| Tag | mFc |
| Products description | Anti-Beta-2 microglobulin (B2M) mouse monoclonal antibody(mAb) is a mouse monoclonal antibody produced by CHO technology.
The antibody is ELISA validated as capture antibody and detection antibody pair.
|
| Specics | mouse |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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