Bovine BNP antibody and antigen (recombinant protein)

Diagnostic anti-Bovine BNP antibodies pairs and antigen for animal health (animal Bovines/Cattle Cardiovascular Disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-BNP-Ag01Bovine BNP$3090.00
GMP-BOV-BNP-Ab01Anti-Bovine BNP mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-BNP-Ab02Anti-Bovine BNP mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-BNP-Ab03Anti-Bovine BNP human monoclonal antibody (mAb)$3090.00
GMP-BOV-BNP-Ab04Anti-Bovine BNP human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-BNP-Ag01
Product NameBovine BNP
Target/BiomarkerBovine BNP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine BNP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in BNP level test of animal Bovines/Cattle with Cardiovascular Disease.
TagHis
Reconized/Reactive SpecicsBovine BNP
Product descriptionRecombinant Bovine BNP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-BNP-Ab01,GMP-BOV-BNP-Ab02
Target/BiomarkerBovine BNP
Product NameAnti-Bovine BNP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine BNP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine BNP antibodies in Bovine BNP level test of animal Bovines/Cattle with Cardiovascular Disease.
Product descriptionAnti-Bovine BNP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine BNP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-BNP-Ab03,GMP-BOV-BNP-Ab04
Target/BiomarkerBovine BNP
Product NameAnti-Bovine BNP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine BNP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine BNP antibodies in Bovine BNP level test of animal Bovines/Cattle with Cardiovascular Disease.
Product descriptionAnti-Bovine BNP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Bovine B-type Natriuretic Peptide, or Bovine BNP, emerges as a remarkable and indispensable component of the cardiovascular system within cattle. Classified within the natriuretic peptide family, Bovine BNP participates actively in the complex orchestration of blood pressure regulation, fluid equilibrium, and the meticulous maintenance of cardiovascular homeostasis. Its production primarily emanates from cardiac cells, specifically the cardiomyocytes dwelling in the ventricles of the bovine heart.

    Structurally, Bovine BNP consists of a chain of amino acids. However, it is in its active form, BNP-32, that it exerts its profound physiological effects. Upon release into the bloodstream, Bovine BNP interacts with specific receptors strategically located in the kidneys and blood vessels, thereby triggering a cascade of responses that significantly impact the circulatory system.

    The synthesis and release of Bovine BNP are intricately linked to the mechanical strains endured by the bovine heart. When the heart experiences elevated pressure or stretching, a common occurrence during various cardiac conditions or physiological states, the cardiac cells respond promptly by liberating Bovine BNP into the bloodstream.

    Bovine BNP, once in its active state, embarks on an array of actions that fundamentally influence cardiovascular physiology. Among its most notable effects is vasodilation, which signifies the relaxation and expansion of blood vessels. This vasodilatory action serves to diminish peripheral vascular resistance, culminating in the reduction of afterload on the heart. Additionally, Bovine BNP promotes diuresis, or enhanced urine production. By facilitating increased excretion of urine, Bovine BNP contributes to the elimination of surplus fluid from the body, concurrently lowering blood volume and further alleviating the workload on the heart.



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