Bovine α-defensin 5 antibody and antigen (recombinant protein)

Diagnostic anti-Bovine α-defensin 5 antibodies pairs and antigen for animal health (animal Bovines/Cattle Prosthetic joint infection (PJI)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Ruminants disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-a-defensin-5-Ag01Bovine α-defensin 5$3090.00
GMP-BOV-a-defensin-5-Ab01Anti-Bovine α-defensin 5 mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-a-defensin-5-Ab02Anti-Bovine α-defensin 5 mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-a-defensin-5-Ab03Anti-Bovine α-defensin 5 human monoclonal antibody (mAb)$3090.00
GMP-BOV-a-defensin-5-Ab04Anti-Bovine α-defensin 5 human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-a-defensin-5-Ag01
Product NameBovine α-defensin 5
Target/BiomarkerBovine α-defensin 5
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine α-defensin 5 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in α-defensin 5 level test of animal Bovines/Cattle with Prosthetic joint infection (PJI).
TagHis
Reconized/Reactive SpecicsBovine α-defensin 5
Product descriptionRecombinant Bovine α-defensin 5 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-a-defensin-5-Ab01,GMP-BOV-a-defensin-5-Ab02
Target/BiomarkerBovine α-defensin 5
Product NameAnti-Bovine α-defensin 5 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine α-defensin 5 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine α-defensin 5 antibodies in Bovine α-defensin 5 level test of animal Bovines/Cattle with Prosthetic joint infection (PJI).
Product descriptionAnti-Bovine α-defensin 5 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine α-defensin 5 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-a-defensin-5-Ab03,GMP-BOV-a-defensin-5-Ab04
Target/BiomarkerBovine α-defensin 5
Product NameAnti-Bovine α-defensin 5 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine α-defensin 5 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine α-defensin 5 antibodies in Bovine α-defensin 5 level test of animal Bovines/Cattle with Prosthetic joint infection (PJI).
Product descriptionAnti-Bovine α-defensin 5 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    α-defensin 5, often referred to as Def5, is a remarkable antimicrobial peptide residing within the bovine (cattle) digestive system. It belongs to the α-defensin family, a group of small cationic peptides celebrated for their potent antimicrobial properties. Within the complex physiology of cattle, α-defensin 5 assumes a pivotal role in the innate immune system, primarily within the gastrointestinal tract.

    The production and secretion of α-defensin 5 primarily occur within specialized cells called Paneth cells. These cells are strategically located in the crypts of Lieberkühn in the small intestine, where they play a crucial role in maintaining intestinal health and defending against potential microbial threats.

    Structurally, α-defensin 5 showcases a unique arrangement of cysteine residues that form disulfide bonds. These bonds not only confer structural stability but also enhance its antimicrobial activity. The primary function of α-defensin 5 is to target and neutralize a broad spectrum of pathogens, including bacteria, viruses, and fungi. By disrupting the integrity of microbial cell membranes, α-defensin 5 assumes a pivotal role in the body's defense against invasive microorganisms.



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