Bovine sST2 antibody and antigen (recombinant protein)

Diagnostic anti-Bovine sST2 antibodies pairs and antigen for animal health (animal Bovines/Cattle chronic and acute heart failure) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Ruminants disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-sST2-Ag01Bovine sST2$3090.00
GMP-BOV-sST2-Ab01Anti-Bovine sST2 mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-sST2-Ab02Anti-Bovine sST2 mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-sST2-Ab03Anti-Bovine sST2 human monoclonal antibody (mAb)$3090.00
GMP-BOV-sST2-Ab04Anti-Bovine sST2 human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-sST2-Ag01
Product NameBovine sST2
Target/BiomarkerBovine sST2
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine sST2 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sST2 level test of animal Bovines/Cattle with chronic and acute heart failure.
TagHis
Reconized/Reactive SpecicsBovine sST2
Product descriptionRecombinant Bovine sST2 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-sST2-Ab01,GMP-BOV-sST2-Ab02
Target/BiomarkerBovine sST2
Product NameAnti-Bovine sST2 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine sST2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine sST2 antibodies in Bovine sST2 level test of animal Bovines/Cattle with chronic and acute heart failure.
Product descriptionAnti-Bovine sST2 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine sST2 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-sST2-Ab03,GMP-BOV-sST2-Ab04
Target/BiomarkerBovine sST2
Product NameAnti-Bovine sST2 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine sST2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine sST2 antibodies in Bovine sST2 level test of animal Bovines/Cattle with chronic and acute heart failure.
Product descriptionAnti-Bovine sST2 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Soluble ST2 (sST2) in cattle represents a multifaceted biomarker intricately intertwined with bovine cardiovascular health. It plays a pivotal role in immune responses, inflammation regulation, and cardiac function, positioning itself as a key player in the complex orchestra of cardiac stress, injury, and recovery.

    To delve deeper, sST2 serves as a receptor for interleukin-33 (IL-33), a cytokine with potent anti-inflammatory and protective effects, particularly within the cardiovascular system. In cattle, sST2 is predominantly secreted by cardiac cells, especially cardiomyocytes. Its soluble form, detectable in the bloodstream, functions as an essential biomarker for assessing cardiac health and identifying underlying cardiac pathologies.

    Elevated sST2 levels in cattle often result from cardiac stress, injury, or inflammation. This makes sST2 a vital tool for diagnosing and monitoring a spectrum of cardiac conditions, ranging from myocarditis (inflammation of the heart muscle) to heart failure and beyond. The dynamic response of sST2 to cardiac strain positions it as a sensitive and precise marker for identifying bovine patients at risk of cardiac disorders.



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