Canine GFAP antibody and antigen (recombinant protein)

Diagnostic anti-Canine GFAP antibodies pairs and antigen for animal health (animal Dog/Canine Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-GFAP-Ag01Canine GFAP$3090.00
GMP-CAN-GFAP-Ab01Anti-Canine GFAP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-GFAP-Ab02Anti-Canine GFAP mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-GFAP-Ab03Anti-Canine GFAP human monoclonal antibody (mAb)$3090.00
GMP-CAN-GFAP-Ab04Anti-Canine GFAP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-GFAP-Ag01
Product NameCanine GFAP
Target/BiomarkerCanine GFAP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine GFAP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GFAP level test of animal Dog/Canine with Alzheimer Disease(AD).
TagHis
Reconized/Reactive SpecicsCanine GFAP
Product descriptionRecombinant Canine GFAP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-GFAP-Ab01,GMP-CAN-GFAP-Ab02
Target/BiomarkerCanine GFAP
Product NameAnti-Canine GFAP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine GFAP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine GFAP antibodies in Canine GFAP level test of animal Dog/Canine with Alzheimer Disease(AD).
Product descriptionAnti-Canine GFAP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine GFAP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-GFAP-Ab03,GMP-CAN-GFAP-Ab04
Target/BiomarkerCanine GFAP
Product NameAnti-Canine GFAP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine GFAP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine GFAP antibodies in Canine GFAP level test of animal Dog/Canine with Alzheimer Disease(AD).
Product descriptionAnti-Canine GFAP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Canine GFAP, or Glial Fibrillary Acidic Protein, stands as a sentinel within the intricate realm of canine neurobiology. This protein, primarily residing in astrocytes within the central nervous system (CNS) of dogs, plays multifaceted roles in maintaining the structural and functional integrity of the nervous system.

    Structurally, Canine GFAP is a member of the intermediate filament protein family, sharing genetic and functional homology with its counterparts in diverse species, including humans. Astrocytes, the primary cellular reservoir of GFAP, rely on this protein for structural support and cytoskeletal integrity. Canine GFAP filaments form a complex network within astrocytes, contributing to their resilience and capacity to respond to various challenges.

    Functionally, Canine GFAP is instrumental in astrocyte-mediated processes that support neuronal health. Astrocytes nourish neurons, regulate synaptic transmission, modulate neurotransmitter levels, and maintain the blood-brain barrier. Canine GFAP actively participates in these functions, ensuring the optimal functioning of the CNS.

    However, the significance of Canine GFAP extends beyond its structural and homeostatic roles. In response to CNS injury, neuroinflammation, or neurodegenerative conditions, astrocytes undergo a transformative process known as astrogliosis. During astrogliosis, astrocytes become activated, leading to increased expression of GFAP. This upregulation serves as a protective and reparative response, as astrocytes encapsulate injured areas, isolate toxic substances, and support neuronal recovery.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.