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Canine NFL antibody and antigen (recombinant protein)
Diagnostic anti-Canine NFL antibodies pairs and antigen for animal health (animal Dog/Canine Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-CAN-NFL-Ag01 | Canine NFL | $3090.00 |
| GMP-CAN-NFL-Ab01 | Anti-Canine NFL mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-NFL-Ab02 | Anti-Canine NFL mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-NFL-Ab03 | Anti-Canine NFL human monoclonal antibody (mAb) | $3090.00 |
| GMP-CAN-NFL-Ab04 | Anti-Canine NFL human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-CAN-NFL-Ag01 |
| Product Name | Canine NFL |
| Target/Biomarker | Canine NFL |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Canine NFL antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in NFL level test of animal Dog/Canine with Alzheimer Disease(AD). |
| Tag | His | Reconized/Reactive Specics | Canine NFL |
| Product description | Recombinant Canine NFL protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-NFL-Ab01,GMP-CAN-NFL-Ab02 |
| Target/Biomarker | Canine NFL |
| Product Name | Anti-Canine NFL mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Canine NFL antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine NFL antibodies in Canine NFL level test of animal Dog/Canine with Alzheimer Disease(AD). |
| Product description | Anti-Canine NFL mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine NFL antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-CAN-NFL-Ab03,GMP-CAN-NFL-Ab04 |
| Target/Biomarker | Canine NFL |
| Product Name | Anti-Canine NFL human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Canine NFL antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine NFL antibodies in Canine NFL level test of animal Dog/Canine with Alzheimer Disease(AD). |
| Product description | Anti-Canine NFL mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Canine Neurofilament Light Chain (NFL) represents a remarkable molecule in canine neurobiology, assuming a pivotal role in the maintenance of neuronal integrity and the assessment of neurological health in dogs. Structurally, NFL is a component of the neurofilament protein family, characterized by its filamentous nature and exclusive presence in the axons of neurons. Its primary function lies in providing structural support to neurons and facilitating efficient electrical signal transmission.
NFL's significance amplifies in situations of neuronal injury or degeneration. When neurons are compromised due to various factors, including trauma, neurodegenerative disorders, or inflammation, NFL undergoes release from the damaged axons. These released NFL molecules enter the cerebrospinal fluid (CSF) and bloodstream, making it a quantifiable biomarker for neuronal damage.
The dynamics of NFL release and measurement underscore its clinical relevance in the field of veterinary neurology. Elevated NFL levels signify ongoing neuronal damage or degeneration, often observed in conditions such as traumatic brain injury (TBI), spinal cord injury (SCI), canine degenerative myelopathy (CDM), and inflammatory disorders of the nervous system.
About GDU
GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
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