Canine S100-A9 antibody and antigen (recombinant protein)

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-CAN-S100-A9-Ag01	Recombinant Canine S100-A9 protein	3090
GMP-CAN-S100-A9-Ab01	Anti-Canine S100-A9 mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-S100-A9-Ab02	Anti-Canine S100-A9 mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-S100-A9-Ab03	Anti-Canine S100-A9 mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-S100-A9-Ab04	Anti-Canine S100-A9 mouse monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-CAN-S100-A9-Ag01
Product Name	Recombinant Canine S100-A9 protein
Target/Biomarker	Canine Calprotectin heavy chain (S100-A9)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Calprotectin heavy chain antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100-A9 level test of animal Dog/Canine with inflammatory bowel disease.
Tag	His
Products description	Recombinant Canine S100-A9 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-S100-A9-Ab01, GMP-CAN-S100-A9-Ab02, GMP-CAN-S100-A9-Ab03, GMP-CAN-S100-A9-Ab04
Product Name	Anti-Canine S100-A9 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Calprotectin heavy chain (S100-A9)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Anti-Canine Calprotectin heavy chain antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100-A9 level test of animal Dog/Canine with inflammatory bowel disease.
Tag	mFc
Products description	Anti-Canine S100-A9 mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

S100-A9, also known as calgranulin B, is a calcium-binding protein belonging to the S100 protein family, renowned for its involvement in a myriad of cellular processes, particularly those related to inflammation and immune responses. In dogs (canines), S100-A9 is a key player in innate immunity, primarily produced by neutrophils and monocytes. The significance of S100-A9 lies in its ability to form a heterodimeric complex with S100-A8, collectively known as S100A8/A9 or calprotectin. This complex serves as a critical component of the innate immune system's arsenal, playing multifaceted roles in immune regulation, host defense, and tissue homeostasis. The release of S100A8/A9 occurs primarily in response to inflammatory cues. Activated neutrophils and monocytes release this complex into the extracellular milieu as part of the innate immune response. S100A8/A9, once externalized, acts as a potent pro-inflammatory mediator, capable of initiating and amplifying immune responses. Its functions include the recruitment of immune cells to sites of infection or injury and the facilitation of phagocytosis, a crucial process by which immune cells engulf and eliminate pathogens. Additionally, S100-A9 has been implicated in other cellular processes beyond inflammation. It plays a role in cell adhesion, differentiation, and tissue repair. As a damage-associated molecular pattern (DAMP) molecule, S100-A9 serves as a sentinel, alerting the immune system to tissue damage or infection. This multifunctional nature underscores its significance in canine physiology and immunology.

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