Canine S100-A9 antibody and antigen (recombinant protein)

Diagnostic anti-Canine S100-A9 antibodies pairs and antigen for animal health (animal Dog/Canine inflammatory bowel disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-CAN-S100-A9-Ag01Canine S100-A9$3090.00
GMP-CAN-S100-A9-Ab01Anti-Canine S100-A9 mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-S100-A9-Ab02Anti-Canine S100-A9 mouse monoclonal antibody (mAb)$3090.00
GMP-CAN-S100-A9-Ab03Anti-Canine S100-A9 human monoclonal antibody (mAb)$3090.00
GMP-CAN-S100-A9-Ab04Anti-Canine S100-A9 human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-CAN-S100-A9-Ag01
Product NameCanine S100-A9
Target/BiomarkerCanine S100-A9
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Canine S100-A9 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100-A9 level test of animal Dog/Canine with inflammatory bowel disease.
TagHis
Reconized/Reactive SpecicsCanine S100-A9
Product descriptionRecombinant Canine S100-A9 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-S100-A9-Ab01,GMP-CAN-S100-A9-Ab02
Target/BiomarkerCanine S100-A9
Product NameAnti-Canine S100-A9 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Canine S100-A9 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine S100-A9 antibodies in Canine S100-A9 level test of animal Dog/Canine with inflammatory bowel disease.
Product descriptionAnti-Canine S100-A9 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine S100-A9 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-CAN-S100-A9-Ab03,GMP-CAN-S100-A9-Ab04
Target/BiomarkerCanine S100-A9
Product NameAnti-Canine S100-A9 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Canine S100-A9 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Canine S100-A9 antibodies in Canine S100-A9 level test of animal Dog/Canine with inflammatory bowel disease.
Product descriptionAnti-Canine S100-A9 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    S100-A9, also known as calgranulin B, is a calcium-binding protein belonging to the S100 protein family, renowned for its involvement in a myriad of cellular processes, particularly those related to inflammation and immune responses. In dogs (canines), S100-A9 is a key player in innate immunity, primarily produced by neutrophils and monocytes.

    The significance of S100-A9 lies in its ability to form a heterodimeric complex with S100-A8, collectively known as S100A8/A9 or calprotectin. This complex serves as a critical component of the innate immune system's arsenal, playing multifaceted roles in immune regulation, host defense, and tissue homeostasis.

    The release of S100A8/A9 occurs primarily in response to inflammatory cues. Activated neutrophils and monocytes release this complex into the extracellular milieu as part of the innate immune response. S100A8/A9, once externalized, acts as a potent pro-inflammatory mediator, capable of initiating and amplifying immune responses. Its functions include the recruitment of immune cells to sites of infection or injury and the facilitation of phagocytosis, a crucial process by which immune cells engulf and eliminate pathogens.

    Additionally, S100-A9 has been implicated in other cellular processes beyond inflammation. It plays a role in cell adhesion, differentiation, and tissue repair. As a damage-associated molecular pattern (DAMP) molecule, S100-A9 serves as a sentinel, alerting the immune system to tissue damage or infection. This multifunctional nature underscores its significance in canine physiology and immunology.



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