Equine α-defensin 5 antibody and antigen (recombinant protein)
Diagnostic anti-Equine α-defensin 5 antibodies pairs and antigen for animal health (animal Equine/Horse Prosthetic joint infection (PJI)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-EQU-a-defensin-5-Ag01 | Equine α-defensin 5 | $3090.00 |
GMP-EQU-a-defensin-5-Ab01 | Anti-Equine α-defensin 5 mouse monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-a-defensin-5-Ab02 | Anti-Equine α-defensin 5 mouse monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-a-defensin-5-Ab03 | Anti-Equine α-defensin 5 human monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-a-defensin-5-Ab04 | Anti-Equine α-defensin 5 human monoclonal antibody (mAb) | $3090.00 |
Size: 1mg | 10mg | 100mg
Product Description
Cat No. | GMP-EQU-a-defensin-5-Ag01 |
Product Name | Equine α-defensin 5 |
Target/Biomarker | Equine α-defensin 5 |
Expression platform | E.coli |
Isotypes | Recombinant Antigen |
Bioactivity validation | Anti-Equine α-defensin 5 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in α-defensin 5 level test of animal Equine/Horse with Prosthetic joint infection (PJI). |
Tag | His | Reconized/Reactive Specics | Equine α-defensin 5 |
Product description | Recombinant Equine α-defensin 5 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-EQU-a-defensin-5-Ab01,GMP-EQU-a-defensin-5-Ab02 |
Target/Biomarker | Equine α-defensin 5 |
Product Name | Anti-Equine α-defensin 5 mouse monoclonal antibody (mAb) |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Recombinant Equine α-defensin 5 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine α-defensin 5 antibodies in Equine α-defensin 5 level test of animal Equine/Horse with Prosthetic joint infection (PJI). |
Product description | Anti-Equine α-defensin 5 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine α-defensin 5 antibodies. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-EQU-a-defensin-5-Ab03,GMP-EQU-a-defensin-5-Ab04 |
Target/Biomarker | Equine α-defensin 5 |
Product Name | Anti-Equine α-defensin 5 human monoclonal antibody (mAb) |
Expression platform | CHO |
Isotypes | Human lgG1 |
Bioactivity validation | Recombinant Equine α-defensin 5 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine α-defensin 5 antibodies in Equine α-defensin 5 level test of animal Equine/Horse with Prosthetic joint infection (PJI). |
Product description | Anti-Equine α-defensin 5 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
α-defensin 5, commonly referred to as Def5, is a remarkable antimicrobial peptide residing within the equine (horse) digestive system. It belongs to the α-defensin family, a group of small cationic peptides renowned for their potent antimicrobial properties. In horses, α-defensin 5 plays a pivotal role in the innate immune system, primarily within the gastrointestinal tract.
The production and secretion of α-defensin 5 primarily occur within specialized cells called Paneth cells. These cells are strategically located in the crypts of Lieberkühn in the small intestine, where they contribute significantly to maintaining intestinal health and defending against potential microbial threats.
Structurally, α-defensin 5 boasts a unique configuration of cysteine residues that form disulfide bonds. These bonds not only confer structural stability but also enhance its antimicrobial activity. The primary function of α-defensin 5 is to target and neutralize a wide spectrum of pathogens, including bacteria, viruses, and fungi. By disrupting the integrity of microbial cell membranes, α-defensin 5 plays a pivotal role in the body's defense against invasive microorganisms.
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