Equine cTnI antibody and antigen (recombinant protein)

Diagnostic anti-Equine cTnI antibodies pairs and antigen for animal health (animal Equine/Horse Myocardial injury, heart disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-cTnI-Ag01Equine cTnI$3090.00
GMP-EQU-cTnI-Ab01Anti-Equine cTnI mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-cTnI-Ab02Anti-Equine cTnI mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-cTnI-Ab03Anti-Equine cTnI human monoclonal antibody (mAb)$3090.00
GMP-EQU-cTnI-Ab04Anti-Equine cTnI human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-cTnI-Ag01
Product NameEquine cTnI
Target/BiomarkerEquine cTnI
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine cTnI antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cTnI level test of animal Equine/Horse with Myocardial injury, heart disease.
TagHis
Reconized/Reactive SpecicsEquine cTnI
Product descriptionRecombinant Equine cTnI protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-cTnI-Ab01,GMP-EQU-cTnI-Ab02
Target/BiomarkerEquine cTnI
Product NameAnti-Equine cTnI mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine cTnI antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine cTnI antibodies in Equine cTnI level test of animal Equine/Horse with Myocardial injury, heart disease.
Product descriptionAnti-Equine cTnI mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine cTnI antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-cTnI-Ab03,GMP-EQU-cTnI-Ab04
Target/BiomarkerEquine cTnI
Product NameAnti-Equine cTnI human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine cTnI antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine cTnI antibodies in Equine cTnI level test of animal Equine/Horse with Myocardial injury, heart disease.
Product descriptionAnti-Equine cTnI mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Cardiac Troponin I (cTnI) is a protein of exceptional significance in the context of equine physiology. This cardiac-specific biomarker is predominantly found in the bloodstream of horses (equines) and serves as a crucial indicator of cardiac health. To truly appreciate the role of cTnI, it is essential to delve into its structural composition, functional significance, and its position within the realm of equine cardiology.

    Structurally, cTnI is one of the three subunits of the troponin complex, the other two being cardiac Troponin T (cTnT) and cardiac Troponin C (cTnC). The troponin complex resides within the sarcomeres of cardiac muscle fibers, where it meticulously regulates muscle contraction. This precision is vital for the rhythmic and efficient pumping of blood by the horse's heart.

    What distinguishes cTnI is its exclusive cardiac specificity. While other troponin isoforms exist in skeletal muscle, cTnI is uniquely expressed in the heart. This specificity makes cTnI an exceptionally valuable biomarker for assessing cardiac muscle injury or damage. When cardiac cells are compromised due to factors such as Myocardial injury, heart disease, cardiac diseases, or cardiac trauma, cTnI is released into the bloodstream. Therefore, elevated levels of cTnI in a horse's blood can serve as a critical diagnostic indicator of cardiac health.

    Detecting cTnI levels in equine serum is typically achieved through immunoassays, such as enzyme-linked immunosorbent assays (ELISA). These assays provide a quantitative measure of cTnI concentration, enabling veterinarians to assess the extent of cardiac injury or disease. The sensitivity of these assays is such that even minor myocardial damage can lead to detectable elevations in cTnI levels, allowing for early diagnosis and intervention.



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