Feline H-FABP antibody and antigen (recombinant protein)

Diagnostic anti-Feline H-FABP antibodies pairs and antigen for animal health (animal Cat/Feline myocardial injury) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Companion Animal disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-H-FABP-Ag01Feline H-FABP$3090.00
GMP-FEL-H-FABP-Ab01Anti-Feline H-FABP mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-H-FABP-Ab02Anti-Feline H-FABP mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-H-FABP-Ab03Anti-Feline H-FABP human monoclonal antibody (mAb)$3090.00
GMP-FEL-H-FABP-Ab04Anti-Feline H-FABP human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-H-FABP-Ag01
Product NameFeline H-FABP
Target/BiomarkerFeline H-FABP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline H-FABP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in H-FABP level test of animal Cat/Feline with myocardial injury.
TagHis
Reconized/Reactive SpecicsFeline H-FABP
Product descriptionRecombinant Feline H-FABP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-H-FABP-Ab01,GMP-FEL-H-FABP-Ab02
Target/BiomarkerFeline H-FABP
Product NameAnti-Feline H-FABP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline H-FABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline H-FABP antibodies in Feline H-FABP level test of animal Cat/Feline with myocardial injury.
Product descriptionAnti-Feline H-FABP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline H-FABP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-H-FABP-Ab03,GMP-FEL-H-FABP-Ab04
Target/BiomarkerFeline H-FABP
Product NameAnti-Feline H-FABP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline H-FABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline H-FABP antibodies in Feline H-FABP level test of animal Cat/Feline with myocardial injury.
Product descriptionAnti-Feline H-FABP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    H-FABP, Heart-Fatty Acid Binding Protein, represents a remarkable biomarker within the feline (cat) physiology landscape. This small but pivotal protein finds its predominant expression within the heart muscle, or cardiomyocytes, where it plays a central role in the regulation of fatty acid metabolism. Structurally, H-FABP is a cytoplasmic protein endowed with a unique binding site that enables it to ferry fatty acids—a vital energy source—within the cardiac muscle cells.

    The exclusive localization of H-FABP within the feline heart underscores its critical importance in assessing cardiac health. Under normal circumstances, H-FABP levels in a cat's bloodstream remain relatively low. However, its concentration can surge significantly in response to cardiac stress or injury, rendering it a highly sensitive and specific diagnostic tool for veterinarians and a source of invaluable insights for feline owners.

    H-FABP's functional significance within the heart is multifaceted. It actively participates in the uptake, transport, and utilization of fatty acids as an energy substrate, a process vital for sustaining cardiac contractility and function. However, it is its role as a biomarker that truly shines when the heart faces challenges.

    When cardiac ischemia or infarction, such as a heart attack, occurs, the heart muscle experiences injury due to insufficient blood supply. This ischemic injury triggers the release of H-FABP into the bloodstream. Consequently, elevated levels of H-FABP in a cat's blood can serve as an early indicator of myocardial damage, even before clinical symptoms manifest.



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