Feline NSE antibody and antigen (recombinant protein)

Diagnostic anti-Feline NSE antibodies pairs and antigen for animal health (animal Cat/Feline neuroendocrine tumors) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-NSE-Ag01Feline NSE$3090.00
GMP-FEL-NSE-Ab01Anti-Feline NSE mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-NSE-Ab02Anti-Feline NSE mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-NSE-Ab03Anti-Feline NSE human monoclonal antibody (mAb)$3090.00
GMP-FEL-NSE-Ab04Anti-Feline NSE human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-NSE-Ag01
Product NameFeline NSE
Target/BiomarkerFeline NSE
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline NSE antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in NSE level test of animal Cat/Feline with neuroendocrine tumors.
TagHis
Reconized/Reactive SpecicsFeline NSE
Product descriptionRecombinant Feline NSE protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-NSE-Ab01,GMP-FEL-NSE-Ab02
Target/BiomarkerFeline NSE
Product NameAnti-Feline NSE mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline NSE antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline NSE antibodies in Feline NSE level test of animal Cat/Feline with neuroendocrine tumors.
Product descriptionAnti-Feline NSE mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline NSE antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-NSE-Ab03,GMP-FEL-NSE-Ab04
Target/BiomarkerFeline NSE
Product NameAnti-Feline NSE human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline NSE antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline NSE antibodies in Feline NSE level test of animal Cat/Feline with neuroendocrine tumors.
Product descriptionAnti-Feline NSE mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Cat/Feline Neuron-Specific Enolase (NSE) represents a fascinating facet of feline neurobiology. It is a specialized form of the enolase enzyme, which in its various isoforms, plays a multifaceted role in cellular metabolism. In the context of feline physiology, NSE stands out as a key player in the intricate machinery of neuronal energy production.

    Within the neurons of the feline nervous system, NSE takes on a central role. It is actively involved in glycolysis, a fundamental metabolic pathway responsible for converting glucose into pyruvate, a critical intermediate in cellular respiration. Through glycolysis, cells generate adenosine triphosphate (ATP), the universal energy currency of living organisms. NSE's involvement in this energy-generating process underscores its significance in sustaining the high energy demands of neurons.

    Beyond its metabolic function, NSE contributes to the structural integrity of neurons. Neurons are specialized cells with unique structural adaptations that allow them to transmit electrical impulses over long distances. NSE, localized primarily in the cytoplasm, helps maintain the cytoskeletal framework of neurons, ensuring their proper shape and function.

    The distinctive feature of NSE is its neuron-specificity. While other enolase isoforms are found in various cell types, NSE is highly concentrated in neurons and neuroendocrine cells. This selective distribution makes NSE a valuable marker for neuronal tissue in cats.

    Importantly, under certain circumstances, NSE can find its way into the bloodstream. This occurs when there is damage or injury to neurons, leading to the release of NSE into the extracellular space and eventually into circulation. As such, NSE levels in the blood become a critical indicator of neuronal damage or dysfunction.



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