Mycoplasma capricolum subsp. capripneumoniae antibody and antigen (recombinant protein)

Diagnostic anti-Mycoplasma capricolum subsp. capripneumoniae antibodies pairs and antigen for animal health (animal Ovines/Sheep, Caprine/Goat infectious disease caprine pleuropneumonia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P083-Ag01 Recombinant Mycoplasma capricolum subsp. capripneumoniae protein $3090.00
GMP-VT-P083-Ab01 Anti-Mycoplasma capricolum subsp. capripneumoniae mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P083-Ab02 Anti-Mycoplasma capricolum subsp. capripneumoniae mouse monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P083-Ag01
Product Name Recombinant Mycoplasma capricolum subsp. capripneumoniae protein
Pathogen Mycoplasma capricolum subsp. capripneumoniae
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Mycoplasma capricolum subsp. capripneumoniae antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Mycoplasma capricolum subsp. capripneumoniae level test of animal Ovines/Sheep, Caprine/Goat infectious disease with caprine pleuropneumonia.
Tag His
Product description Recombinant Mycoplasma capricolum subsp. capripneumoniae proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P083-Ab01,GMP-VT-P083-Ab02
Pathogen Mycoplasma capricolum subsp. capripneumoniae
Product Name Anti-Mycoplasma capricolum subsp. capripneumoniae mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Mycoplasma capricolum subsp. capripneumoniae antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Mycoplasma capricolum subsp. capripneumoniae antibodies in Mycoplasma capricolum subsp. capripneumoniae level test of animal Ovines/Sheep, Caprine/Goat infectious disease with caprine pleuropneumonia.
Product description Anti-Mycoplasma capricolum subsp. capripneumoniae mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Mycoplasma capricolum subsp. capripneumoniae antibodies./td>
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Pathogen


    Mycoplasma capricolum subsp. capripneumoniae, commonly known as Mccp, is a pathogen that primarily infects goats, causing a highly contagious respiratory disease known as contagious caprine pleuropneumonia (CCPP). The pathogen is classified under the Mollicutes class and is a member of the Mycoplasmataceae family within the genus Mycoplasma.

    Mycoplasmas are unique, prokaryotic organisms that lack a cell wall. As such, they are resistant to many antibiotics, making them hard to treat. Mycoplasma capricolum subsp. capripneumoniae is an important pathogen of economic importance, as it causes mortality and morbidity in small ruminants, leading to significant losses in the livestock industry.

    The genome of M. capricolum subsp. capripneumoniae has been sequenced, and it has been shown to contain numerous surface proteins that are critical in adhesion, colonization, and virulence. These surface proteins have been identified as putative hemagglutinins, cytadhesins, and glutamate dehydrogenase. Among these, Cpa and PH are considered the most commonly used surface proteins for the diagnosis of CCPP.

    Mycoplasma capricolum subsp. capripneumoniae primarily infects goats, but it can also infect sheep, cattle, and other artiodactyl hosts. The respiratory system is the major route of infection, with transmission occurring through inhalation of droplets or airborne particles from infected animals. The severity of the disease caused by M. capricolum subsp. capripneumoniae depends on various factors, including the virulence of the infecting strain, the host immune status, and environmental factors.

    Contagious caprine pleuropneumonia (CCPP) is the most common disease caused by M. capricolum subsp. capripneumoniae. It is a respiratory disease characterized by labored breathing, fever, and coughing. Other symptoms include nasal discharge, reduced appetite, depression, and weight loss. In severe cases, the disease can lead to death within 1-2 weeks of infection.

    Diagnostic methods play a critical role in the diagnosis, surveillance, and control of CCPP outbreaks. A number of techniques have been developed, with nucleic acid amplification techniques such as PCR and LAMP being the most commonly used. These methods target the genes encoding important surface proteins like Cpa, PH, and GDH. Serological assays such as ELISA can also be used to detect antibodies raised against these surface proteins. In addition to diagnostics, vaccination is an important strategy for preventing and controlling CCPP. Several vaccines have been developed, including live attenuated vaccines and subunit vaccines that target specific surface proteins.

    In conclusion, Mycoplasma capricolum subsp. capripneumoniae is a pathogen that is of significant economic importance in the livestock industry as it causes contagious caprine pleuropneumonia in small ruminants. Diagnostic methods, including nucleic acid amplification techniques and serological assays, play a crucial role in the diagnosis, surveillance, and control of the disease. Vaccination is also an important strategy for preventing and controlling CCPP outbreaks.



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