swine vesicular disease virus antibody and antigen (recombinant protein)

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Diagnostic anti-swine vesicular disease virus antibodies pairs and antigen for animal health (animal Swine/Porcine/Pig infectious disease Swine vesicular disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P133-Ag01	Recombinant swine vesicular disease virus protein	$3090.00
GMP-VT-P133-Ab01	Anti-swine vesicular disease virus mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P133-Ab02	Anti-swine vesicular disease virus mouse monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P133-Ag01
Product Name	Recombinant swine vesicular disease virus protein
Pathogen	swine vesicular disease virus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-swine vesicular disease virus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in swine vesicular disease virus level test of animal Swine/Porcine/Pig infectious disease with Swine vesicular disease.
Tag	His
Product description	Recombinant swine vesicular disease virus proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P133-Ab01,GMP-VT-P133-Ab02
Pathogen	swine vesicular disease virus
Product Name	Anti-swine vesicular disease virus mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant swine vesicular disease virus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-swine vesicular disease virus antibodies in swine vesicular disease virus level test of animal Swine/Porcine/Pig infectious disease with Swine vesicular disease.
Product description	Anti-swine vesicular disease virus mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-swine vesicular disease virus antibodies./td>
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen

Swine Vesicular Disease Virus (SVDV): An In-Depth Exploration

Swine Vesicular Disease Virus, or SVDV, is a notable pathogen that primarily affects swine, causing a condition known as Swine Vesicular Disease (SVD). Scientifically classified within the Picornaviridae family, this virus is characterized by its unique features, including its genetic structure, host range, and diagnostic methods.

Classification and Structure of SVDV:

SVDV belongs to the Picornaviridae family, which is a group of viruses known for their small size and non-enveloped nature. The family encompasses a diverse range of viruses that infect various hosts, including humans and animals. SVDV, specifically, is categorized as an RNA virus, as its genetic material consists of a single-stranded RNA genome. It falls under the enterovirus genus, a subgroup within the Picornaviridae family. The viral particle itself is composed of structural and non-structural proteins. Notably, the capsid structure is formed by four major structural proteins: VP1, VP2, VP3, and VP4. VP1, in particular, plays a crucial role in the virus's biology due to its antigenic properties.

Host Range and Disease Impact:

Swine, particularly domesticated pigs, are the primary hosts susceptible to SVDV. The infection with SVDV can have significant economic implications in the swine industry. SVDV primarily targets pigs, and the resultant Swine Vesicular Disease manifests as a range of clinical symptoms. Affected pigs exhibit vesicular lesions in various areas, notably the mouth, snout, feet, and teats. These vesicles can lead to lameness, as they affect the pig's ability to walk and feed. Reduced productivity in affected pigs, along with the potential for transmission to other animals, makes SVD a concern for the agricultural sector and a target for disease control measures.

Diagnostic Methods:

Accurate diagnosis of SVDV is vital for disease control and prevention. Several diagnostic methods are employed for this purpose, often combining serological, antigen detection, and molecular techniques. These methods are essential for prompt and precise identification of the virus.

Serological Tests: Serological tests are instrumental in identifying antibodies produced by the host in response to SVDV infection. By detecting these antibodies, such as immunoglobulin M (IgM) and immunoglobulin G (IgG), in the blood or serum of the affected pigs, it is possible to confirm a previous or current SVDV infection.

Antigen Detection: Antigen detection methods focus on identifying specific viral proteins within the host. These proteins can be detected in various samples, such as vesicular fluid or tissue specimens, using techniques like enzyme-linked immunosorbent assay (ELISA). The presence of viral antigens indicates an active SVDV infection.

Molecular Techniques (RT-PCR): Molecular methods, specifically Reverse Transcription Polymerase Chain Reaction (RT-PCR), offer a highly sensitive and specific means of directly detecting and characterizing SVDV. RT-PCR targets specific regions of the SVDV genome, with the VP1 gene being a common choice. Other conserved genomic regions may also be selected for greater accuracy in virus identification. This technique is particularly valuable for early detection and confirmation of SVDV infection.

In conclusion, Swine Vesicular Disease Virus (SVDV) is a noteworthy pathogen within the Picornaviridae family. Understanding its classification, structure, host range, and diagnostic methods is critical for managing and controlling Swine Vesicular Disease in swine populations. The accurate diagnosis of SVDV, facilitated by serological, antigen detection, and molecular techniques, is essential for implementing timely measures to prevent its spread and mitigate its economic impact on the swine industry.

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