Avian Influenza Virus Type A H3N2 subtype antibody and antigen (recombinant protein)

Diagnostic anti-Avian Influenza Virus Type A H3N2 subtype antibodies pairs and antigen for animal health (animal Avian/Bird/Poultry infectious disease Avian influenza) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P186-Ag01 Recombinant Avian Influenza Virus Type A H3N2 subtype protein $3090.00
GMP-VT-P186-Ab01 Anti-Avian Influenza Virus Type A H3N2 subtype mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P186-Ab02 Anti-Avian Influenza Virus Type A H3N2 subtype mouse monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P186-Ag01
Product Name Recombinant Avian Influenza Virus Type A H3N2 subtype protein
Pathogen Avian Influenza Virus Type A H3N2 subtype
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Avian Influenza Virus Type A H3N2 subtype antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Avian Influenza Virus Type A H3N2 subtype level test of animal Avian/Bird/Poultry infectious disease with Avian influenza.
Tag His
Product description Recombinant Avian Influenza Virus Type A H3N2 subtype proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P186-Ab01,GMP-VT-P186-Ab02
Pathogen Avian Influenza Virus Type A H3N2 subtype
Product Name Anti-Avian Influenza Virus Type A H3N2 subtype mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Avian Influenza Virus Type A H3N2 subtype antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avian Influenza Virus Type A H3N2 subtype antibodies in Avian Influenza Virus Type A H3N2 subtype level test of animal Avian/Bird/Poultry infectious disease with Avian influenza.
Product description Anti-Avian Influenza Virus Type A H3N2 subtype mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avian Influenza Virus Type A H3N2 subtype antibodies./td>
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


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    Pathogen


    Avian Influenza Virus Type A H3N2 subtype is a highly infectious virus that primarily affects birds but can also infect other animals, including pigs and humans. The virus belongs to the Orthomyxoviridae family and has a spherical shape with an envelope. Its genome consists of eight single-stranded RNA segments that encode for 11 different proteins, including hemagglutinin (HA) and neuraminidase (NA), which play a critical role in the virus's replication and pathogenesis.

    The virus has a complex structure consisting of a lipid bilayer envelope that surrounds helical nucleocapsids composed of viral RNA and nucleoprotein. The HA protein is a glycoprotein that binds to sialic acid receptors on host cells and facilitates the entry of the virus into the host cell. The NA protein, another glycoprotein, cleaves these receptors, promoting the release of new virions from infected cells.

    In birds, Avian Influenza Virus Type A H3N2 can cause a highly contagious and often fatal disease known as avian influenza or bird flu. The disease can affect all species of birds, including poultry and wild birds. The clinical signs of the disease vary depending on the severity of the infection and the bird species affected. Infected birds may show signs such as sudden death, respiratory distress, coughing, sneezing, nasal discharge, and decreased egg production.

    In humans, the virus can cause a range of respiratory illnesses, from mild, flu-like symptoms to severe acute respiratory distress syndrome (ARDS), and even death. The symptoms of the illness in humans depend on the age and health status of the patient, the viral dose, and the viral subtype. Avian Influenza Virus Type A H3N2 can infect humans through direct contact with infected poultry or their secretions, or through inhalation of contaminated air or dust. Human-to-human transmission of the virus is rare, but it is possible, especially in close contact with infected individuals.

    The diagnosis of Avian Influenza Virus Type A H3N2 infection is based on clinical signs, history, and laboratory tests. The clinical signs of the disease in birds and humans are variable and non-specific, making laboratory testing critical for diagnosis. Several diagnostic methods are available, including molecular assays such as RT-PCR, qPCR, and LAMP, which target specific regions of the viral genome, primarily the HA and NA genes. Serological assays that detect antibodies against the virus and viral culture techniques can also be employed. Rapid antigen detection tests (RADTs) are also available but have lower sensitivity and specificity compared to molecular assays. The choice of diagnostic method depends on the intended use, clinical context, and available resources.

    Preventing the spread of Avian Influenza Virus Type A H3N2 is critical for protecting both animal and human health. In birds, control measures include vaccination, biosecurity measures, and culling infected birds. The World Health Organization recommends that individuals avoid exposure to live poultry or their environments in areas where avian influenza is known to be circulating. Additionally, individuals should practice good hygiene, regularly washing their hands with soap and water, covering their mouth when coughing or sneezing, and avoiding close contact with sick individuals.

    In summary, Avian Influenza Virus Type A H3N2 subtype is a highly infectious virus that primarily affects birds but can also infect other animals and humans. The virus's complex structure and replication strategy make it a formidable pathogen, requiring careful diagnosis and management to control its spread and mitigate its impact on public health.



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