Salmonella Enteritidis antibody and antigen (recombinant protein)
Diagnostic anti-Salmonella Enteritidis antibodies pairs and antigen for animal health (animal Avian/Bird/Poultry infectious disease salmonellosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-VT-P191-Ag01 | Recombinant Salmonella Enteritidis protein | $3090.00 |
GMP-VT-P191-Ab01 | Anti-Salmonella Enteritidis mouse monoclonal antibody (mAb) | $3090.00 |
GMP-VT-P191-Ab02 | Anti-Salmonella Enteritidis mouse monoclonal antibody (mAb) | $3090.00 |
Size: 1mg | 10mg | 100mg
Product Description
Cat No. | GMP-VT-P191-Ag01 |
Product Name | Recombinant Salmonella Enteritidis protein |
Pathogen | Salmonella Enteritidis |
Expression platform | E.coli |
Isotypes | Recombinant Antigen |
Bioactivity validation | Anti-Salmonella Enteritidis antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Salmonella Enteritidis level test of animal Avian/Bird/Poultry infectious disease with salmonellosis. |
Tag | His | Product description | Recombinant Salmonella Enteritidis proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-VT-P191-Ab01,GMP-VT-P191-Ab02 |
Pathogen | Salmonella Enteritidis |
Product Name | Anti-Salmonella Enteritidis mouse monoclonal antibody (mAb) |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Recombinant Salmonella Enteritidis antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Salmonella Enteritidis antibodies in Salmonella Enteritidis level test of animal Avian/Bird/Poultry infectious disease with salmonellosis. |
Product description | Anti-Salmonella Enteritidis mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Salmonella Enteritidis antibodies./td> |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Pathogen
Salmonella Enteritidis, scientifically designated as S. Enteritidis, is a Gram-negative, rod-shaped bacterium that holds a prominent position within the Salmonella genus. This pathogen is well-recognized for its pathogenicity, particularly in the context of causing foodborne illnesses in humans. In this detailed exploration, we delve into various aspects of Salmonella Enteritidis, encompassing its classification, genetic structure, host specificity, associated diseases, and diagnostic methods.
Pathogen Classification:
S. Enteritidis is unequivocally classified as a prokaryotic bacterium, signifying its status as a single-celled organism without a nucleus or membrane-bound organelles. Taxonomically, this bacterium is situated within the family Enterobacteriaceae, which forms part of the phylum Proteobacteria.
Pathogen Structure:
The genetic architecture of Salmonella Enteritidis is intricate and multifaceted. A pivotal element of its genetic makeup is the Salmonella Pathogenicity Island 1 (SPI-1). SPI-1 represents a genomic region containing genes encoding the Type III secretion system, a crucial apparatus employed by the pathogen for host cell invasion. The invasion process itself is orchestrated by various proteins, among which SipA, SipB, SipC, and SipD, all products of SPI-1, play essential roles. These proteins actively contribute to the bacterium's virulence, mediating interactions with host cells and promoting pathogenicity.
Host Specificity and Associated Diseases:
Salmonella Enteritidis primarily targets two main hosts: humans and poultry, with a pronounced predilection for chickens and their eggs. In addition to its primary hosts, this bacterium has the potential to infect various other animal species, a feature that underscores its significance as a zoonotic pathogen.
The diseases attributed to Salmonella Enteritidis are diverse, although its most common clinical manifestation in humans is gastroenteritis. Gastroenteritis is characterized by a range of gastrointestinal symptoms, including diarrhea, abdominal discomfort, fever, and vomiting. In severe cases, Salmonella Enteritidis infections can progress to systemic infections, notably septicemia, which involves the bacterium's dissemination throughout the bloodstream. Such systemic infections pose a substantial health threat, potentially leading to life-threatening complications.
Diagnostic Methods:
Efficient and accurate diagnostic methods for Salmonella Enteritidis are pivotal for public health, food safety, and disease management. These methods encompass both conventional culture-based techniques and advanced molecular approaches, with a significant focus on Polymerase Chain Reaction (PCR).
Culture-Based Techniques: Conventional culture-based methods involve isolating the bacterium from clinical or food samples. Selective culture media tailored to Salmonella species are utilized to promote bacterial growth. Confirmation of the pathogen's identity is subsequently achieved through biochemical tests.
Molecular Methods, Including PCR: Molecular diagnostic techniques, especially PCR, have revolutionized the rapid and specific detection of Salmonella Enteritidis. PCR assays are designed to target specific genes or genetic sequences unique to the pathogen. Among the most commonly targeted genes are invA, a gene highly conserved among Salmonella species, and rfbJ, a gene that serves as a specific marker for S. Enteritidis. Additional targets may encompass genes such as ttrA and sefA, which are selected for their diagnostic sensitivity and specificity in identifying S. Enteritidis.
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