Avian Metapneumovirus Subtype C NP antibody and antigen (recombinant protein)

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Diagnostic anti-Avian Metapneumovirus Subtype C NP antibodies pairs and antigen for animal health (animal Avian/Bird/Poultry infectious disease Avian metapneumovirus infection) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P197-Tg001-Ag01	Recombinant Avian Metapneumovirus Subtype C NP protein	$3090.00
GMP-VT-P197-Tg001-Ab01	Anti-Avian Metapneumovirus Subtype C NP mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P197-Tg001-Ab02	Anti-Avian Metapneumovirus Subtype C NP mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P197-Tg001-Ab03	Anti-Avian Metapneumovirus Subtype C NP human monoclonal antibody (mAb)	$3090.00
GMP-VT-P197-Tg001-Ab04	Anti-Avian Metapneumovirus Subtype C NP human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P197-Tg001-Ag01
Product Name	Recombinant Avian Metapneumovirus Subtype C NP protein
Pathogen	Avian Metapneumovirus Subtype C
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Avian Metapneumovirus Subtype C NP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Avian Metapneumovirus Subtype C level test of animal Avian/Bird/Poultry infectious disease with Avian metapneumovirus infection.
Tag	His
Product description	Recombinant Avian Metapneumovirus Subtype C NP proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P197-Tg001-Ab01,GMP-VT-P197-Tg001-Ab02
Pathogen	Avian Metapneumovirus Subtype C
Product Name	Anti-Avian Metapneumovirus Subtype C NP mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Avian Metapneumovirus Subtype C NP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avian Metapneumovirus Subtype C antibodies in Avian Metapneumovirus Subtype C level test of animal Avian/Bird/Poultry infectious disease with Avian metapneumovirus infection.
Product description	Anti-Avian Metapneumovirus Subtype C NP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avian Metapneumovirus Subtype C antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P197-Tg001-Ab03,GMP-VT-P197-Tg001-Ab04
Pathogen	Avian Metapneumovirus Subtype C
Product Name	Anti-Avian Metapneumovirus Subtype C NP human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Avian Metapneumovirus Subtype C NP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avian Metapneumovirus Subtype C antibodies in Avian Metapneumovirus Subtype C level test of animal Avian/Bird/Poultry infectious disease with Avian metapneumovirus infection.
Product description	Anti-Avian Metapneumovirus Subtype C NP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Avian Metapneumovirus Subtype C (aMPV-C):

Avian Metapneumovirus Subtype C, also referred to as Avian Metapneumovirus type C or Turkey Rhinotracheitis Virus (TRTV), stands as a significant pathogen impacting avian species, particularly the turkey population. This RNA virus belongs to the Pneumoviridae family and the Metapneumovirus genus. Known for its detrimental effects on poultry health, aMPV-C poses economic challenges within the poultry industry due to the respiratory illnesses it induces.

Pathogen Structure:

The genetic blueprint of Avian Metapneumovirus Subtype C comprises a negative-sense, single-stranded RNA genome. The genetic material encodes several vital proteins essential for the virus's function, including the Fusion (F) protein, Hemagglutinin (HN) protein, Phosphoprotein (P), and Nucleoprotein (N). These proteins play crucial roles in various stages of the viral life cycle, such as attachment and entry into host cells, viral replication, and evasion of the host immune response.

Hosts and Diseases:

Avian Metapneumovirus Subtype C predominantly affects domesticated avian species, with turkeys being highly susceptible. The infection commonly results in Turkey Rhinotracheitis (TRT), characterized by respiratory distress, nasal discharge, coughing, and in severe cases, reduced egg production and increased mortality rates in turkey flocks. The impact on the respiratory system can lead to severe economic losses due to reduced productivity and increased veterinary costs in affected poultry flocks.

Transmission and Epidemiology:

Transmission of aMPV-C often occurs via respiratory secretions, direct contact with infected birds, and contaminated surfaces. The virus can survive for a certain period in the environment, contributing to its spread within and between flocks. As a result, strict biosecurity measures are crucial to prevent and control the spread of this pathogen.

Diagnostic Methods:

Numerous diagnostic techniques are employed to identify Avian Metapneumovirus Subtype C in poultry. The primary focus is on detecting viral genetic material (nucleic acids) or the presence of specific antibodies. Common diagnostic methods include:

Reverse Transcription Polymerase Chain Reaction (RT-PCR): This molecular technique amplifies and identifies viral RNA, targeting specific regions of the N or F gene of aMPV-C.

Real-time PCR: Employed for quantification and detection, this method focuses on particular segments of viral RNA, such as the N or F gene, providing quantitative insights into viral load.

Virus Isolation: The virus can be cultured in specific cell lines, confirming its presence by observing characteristic cytopathic effects.

Serological Tests: Enzyme-linked immunosorbent assays (ELISA) and virus-neutralization tests detect antibodies produced in response to Avian Metapneumovirus Subtype C infection.

These diagnostic methodologies play a critical role in surveillance and management of aMPV-C in poultry populations, enabling prompt intervention and implementation of control measures.

In conclusion, Avian Metapneumovirus Subtype C, a significant pathogen in the poultry industry, necessitates thorough understanding, surveillance, and control measures to mitigate its impact on the health and productivity of avian populations. Ongoing research and the advancement of diagnostic methods are crucial in the continued battle against this economically consequential pathogen.

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