Riemerella anatipestifer antibody and antigen (recombinant protein)

Diagnostic anti-Riemerella anatipestifer antibodies pairs and antigen for animal health (animal Goose, Duck infectious disease Duck Septicaemia, Goose 'flu, Riemerellosis, New Duck Disease and Polyserositis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P220-Ag01 Recombinant Riemerella anatipestifer protein $3090.00
GMP-VT-P220-Ab01 Anti-Riemerella anatipestifer mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P220-Ab02 Anti-Riemerella anatipestifer mouse monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P220-Ag01
Product Name Recombinant Riemerella anatipestifer protein
Pathogen Riemerella anatipestifer
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Riemerella anatipestifer antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Riemerella anatipestifer level test of animal Goose, Duck infectious disease with Duck Septicaemia, Goose 'flu, Riemerellosis, New Duck Disease and Polyserositis.
Tag His
Product description Recombinant Riemerella anatipestifer proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P220-Ab01,GMP-VT-P220-Ab02
Pathogen Riemerella anatipestifer
Product Name Anti-Riemerella anatipestifer mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Riemerella anatipestifer antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Riemerella anatipestifer antibodies in Riemerella anatipestifer level test of animal Goose, Duck infectious disease with Duck Septicaemia, Goose 'flu, Riemerellosis, New Duck Disease and Polyserositis.
Product description Anti-Riemerella anatipestifer mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Riemerella anatipestifer antibodies./td>
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Pathogen


    Riemerella anatipestifer: A Comprehensive Examination of the Avian Pathogen

    Introduction:

    Riemerella anatipestifer, a Gram-negative bacterium belonging to the Flavobacteriaceae family, stands as a significant pathogenic threat to avian populations, particularly waterfowl such as ducks and geese. This microorganism is responsible for causing infectious serositis, a highly contagious disease characterized by inflammation of the serous membranes, including the pericardium, pleura, and peritoneum. Understanding the intricate details of this pathogen is essential for devising effective diagnostic and therapeutic strategies to mitigate its impact on avian communities.

    Pathogen Structure and Genetics:

    At the core of Riemerella anatipestifer's pathogenicity lie its genetic components. The bacterium's genome encodes an array of virulence factors crucial for its survival and propagation within the host. Among these, adhesins play a pivotal role in the initial stages of infection, enabling the bacterium to adhere to host cells and establish a foothold. Additionally, toxins produced by Riemerella anatipestifer contribute to the pathogenesis, causing damage to host tissues and triggering the inflammatory response.

    One key element of Riemerella anatipestifer is its outer membrane protein. This protein acts as a multifunctional tool, facilitating interactions with host cells and modulating the host immune response. Its role in immune evasion underscores its significance as a potential target for therapeutic interventions.

    Host Range and Disease Manifestations:

    While waterfowl, particularly ducks and geese, represent the primary hosts of Riemerella anatipestifer, the pathogen is not confined to these species. It can also infect a broader spectrum of avian hosts, leading to diverse disease manifestations. Infectious serositis, the hallmark of Riemerella anatipestifer infection, manifests as respiratory distress, ocular swelling, and increased mortality rates among affected bird populations. The bacterium's ability to cause severe inflammation in the serous membranes significantly contributes to the clinical presentation of the disease.

    Diagnostic Approaches:

    Accurate and timely diagnosis forms the cornerstone of disease management. Several diagnostic methods are employed to identify Riemerella anatipestifer infections. Bacterial culture, a traditional yet reliable technique, aids in isolating the pathogen from clinical samples. Serological assays, focusing on detecting specific antibodies, provide valuable information about the immune response in infected birds.

    In the realm of molecular diagnostics, Polymerase Chain Reaction (PCR) emerges as a powerful tool. PCR-based assays target specific genetic loci within the Riemerella anatipestifer genome. The highly conserved 16S rRNA gene serves as a prominent target for molecular detection, ensuring specificity and accuracy. Moreover, genes associated with virulence, including adhesins and toxins, represent additional targets for PCR-based assays. By amplifying these genetic elements, researchers and diagnosticians can confirm the presence of the pathogen with precision.

    Conclusion:

    Riemerella anatipestifer's impact on avian populations necessitates a comprehensive understanding of its structure, genetics, host interactions, and diagnostic methodologies. Ongoing research endeavors continue to unravel the intricacies of this pathogen, paving the way for innovative solutions in disease prevention and control. By delving into the nuances of Riemerella anatipestifer biology, the scientific community is better equipped to develop targeted interventions, safeguarding the health and well-being of avian species worldwide.



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