Giardia cyst wall protein 1 (CWP1) antibody and antigen (recombinant protein)

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Diagnostic anti-Giardia cyst wall protein 1 (CWP1) antibodies pairs and antigen for animal health (animal Cat/Feline, Dog/Canine, Rabbit, Bovines/Cattle, Equine/Horse, Ovines/Sheep, Caprine/Goat, Fish, Swine/Porcine/Pig, Avian/Bird/Poultry infectious disease Giardiasis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P237-Tg001-Ag01	Recombinant Giardia cyst wall protein 1 (CWP1) protein	$3090.00
GMP-VT-P237-Tg001-Ab01	Anti-Giardia cyst wall protein 1 (CWP1) mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P237-Tg001-Ab02	Anti-Giardia cyst wall protein 1 (CWP1) mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P237-Tg001-Ab03	Anti-Giardia cyst wall protein 1 (CWP1) human monoclonal antibody (mAb)	$3090.00
GMP-VT-P237-Tg001-Ab04	Anti-Giardia cyst wall protein 1 (CWP1) human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P237-Tg001-Ag01
Product Name	Recombinant Giardia cyst wall protein 1 (CWP1) protein
Pathogen	Giardia
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Giardia cyst wall protein 1 (CWP1) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Giardia level test of animal Cat/Feline, Dog/Canine, Rabbit, Bovines/Cattle, Equine/Horse, Ovines/Sheep, Caprine/Goat, Fish, Swine/Porcine/Pig, Avian/Bird/Poultry infectious disease with Giardiasis.
Tag	His
Product description	Recombinant Giardia cyst wall protein 1 (CWP1) proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P237-Tg001-Ab01,GMP-VT-P237-Tg001-Ab02
Pathogen	Giardia
Product Name	Anti-Giardia cyst wall protein 1 (CWP1) mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Giardia cyst wall protein 1 (CWP1) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Giardia antibodies in Giardia level test of animal Cat/Feline, Dog/Canine, Rabbit, Bovines/Cattle, Equine/Horse, Ovines/Sheep, Caprine/Goat, Fish, Swine/Porcine/Pig, Avian/Bird/Poultry infectious disease with Giardiasis.
Product description	Anti-Giardia cyst wall protein 1 (CWP1) mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Giardia antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P237-Tg001-Ab03,GMP-VT-P237-Tg001-Ab04
Pathogen	Giardia
Product Name	Anti-Giardia cyst wall protein 1 (CWP1) human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Giardia cyst wall protein 1 (CWP1) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Giardia antibodies in Giardia level test of animal Cat/Feline, Dog/Canine, Rabbit, Bovines/Cattle, Equine/Horse, Ovines/Sheep, Caprine/Goat, Fish, Swine/Porcine/Pig, Avian/Bird/Poultry infectious disease with Giardiasis.
Product description	Anti-Giardia cyst wall protein 1 (CWP1) mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

Giardia intestinalis (also known as G. lamblia) is a unicellular parasite that belongs to the phylum Diplomonadida. It is found worldwide and causes an infection known as giardiasis, which affects millions of people annually. The parasite has a unique morphology and a complex life cycle that allows it to successfully colonize the small intestine of its host.

Giardia is a eukaryotic microorganism, meaning that it has a membrane-bound nucleus and other membrane-bound organelles such as endoplasmic reticulum and mitochondria. Despite being eukaryotic, Giardia also has some characteristics of prokaryotic organisms, such as a lack of canonical mitosis and the presence of two nuclei per cell.

The morphology of Giardia intestinalis is characterized by the presence of two nuclei, eight flagella, and a ventral adhesive disc. The flagella function in motility, enabling the parasite to swim and migrate through the host's intestine. The adhesive disc serves as a structure for attachment to the host's intestinal cells, allowing the parasite to avoid being expelled from the body through the feces.

Giardiasis, caused by Giardia infection, is one of the most common parasitic infections in humans worldwide. The symptoms of giardiasis include diarrhea, abdominal pain, and weight loss, and can last for several weeks if left untreated. In severe cases, the infection can lead to dehydration and malabsorption of nutrients.

One of the key aspects of diagnosing giardiasis is identifying the presence of Giardia cysts or trophozoites in a stool sample. Stool examination can be done using direct microscopy, immunological assays, or nucleic acid detection techniques such as PCR. Immunological assays target antigens specific to Giardia, while PCR techniques can detect small amounts of Giardia DNA in fecal samples.

The genome of Giardia has been sequenced and its potential proteins, including virulence factors, have been identified. The main genetic component for Giardia is the beta-giardin gene, which is involved in the formation of the actin-rich cytoskeleton and attachment of the parasite to the intestinal lining. Meanwhile, giardin is the main protein involved in cytoskeletal organization and attachment.

In terms of treatment, the standard course of treatment for giardiasis is the use of either metronidazole or tinidazole. These antibiotics work by disrupting DNA synthesis in the parasite and therefore killing it. However, resistance to these antibiotics has emerged, and new drugs are being developed to target Giardia.

Overall, Giardia is an important pathogenic organism that poses a significant public health problem due to its widespread presence and ability to cause infection in humans and other animals. A better understanding of the biology of this unique microorganism could lead to improved diagnostics and treatments for giardiasis, ultimately reducing the global burden of disease caused by this parasite.

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