Salmonella enterica subsp. enterica antibody and antigen (recombinant protein)

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Diagnostic anti-Salmonella enterica subsp. enterica antibodies pairs and antigen for animal health (animal Cat/Feline, Dog/Canine, Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig, Avian/Bird/Poultry infectious disease typhoid) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P275-Ag01	Recombinant Salmonella enterica subsp. enterica protein	$3090.00
GMP-VT-P275-Ab01	Anti-Salmonella enterica subsp. enterica mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P275-Ab02	Anti-Salmonella enterica subsp. enterica mouse monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P275-Ag01
Product Name	Recombinant Salmonella enterica subsp. enterica protein
Pathogen	Salmonella enterica subsp. enterica
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Salmonella enterica subsp. enterica antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Salmonella enterica subsp. enterica level test of animal Cat/Feline, Dog/Canine, Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig, Avian/Bird/Poultry infectious disease with typhoid.
Tag	His
Product description	Recombinant Salmonella enterica subsp. enterica proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P275-Ab01,GMP-VT-P275-Ab02
Pathogen	Salmonella enterica subsp. enterica
Product Name	Anti-Salmonella enterica subsp. enterica mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Salmonella enterica subsp. enterica antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Salmonella enterica subsp. enterica antibodies in Salmonella enterica subsp. enterica level test of animal Cat/Feline, Dog/Canine, Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig, Avian/Bird/Poultry infectious disease with typhoid.
Product description	Anti-Salmonella enterica subsp. enterica mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Salmonella enterica subsp. enterica antibodies./td>
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen

Salmonella enterica subsp. enterica, commonly referred to as Salmonella enterica, is a pathogenic bacterium with a significant impact on both human and animal health due to its ability to cause a range of gastrointestinal infections, most notably salmonellosis. This bacterium belongs to the Enterobacteriaceae family and is characterized as a Gram-negative, facultatively anaerobic organism. In this article, we will delve into its classification, genome structure, and the diseases it causes.

Pathogen Classification:

Salmonella enterica subsp. enterica falls under the domain Bacteria and is a prokaryotic bacterium. It is classified within the Enterobacteriaceae family, a diverse group of bacteria known for their Gram-negative cell structure. Within this family, Salmonella enterica stands out as a pathogen of significant concern in both medical and veterinary contexts.

Pathogen Structure (Main Genes and Proteins):

This bacterium possesses a structurally complex genome, housing a multitude of genes and proteins that contribute to its pathogenicity. These genetic elements are responsible for various aspects of Salmonella enterica's biology, including its ability to infect hosts, evade the host immune system, and cause disease. Notably, Salmonella enterica harbors genes associated with virulence, metabolic functions, and antimicrobial resistance.

Among the proteins that play a pivotal role in Salmonella enterica's pathogenicity is the Type III Secretion System (T3SS). This protein complex is a key virulence factor that facilitates the bacterium's invasion of host cells. It allows Salmonella enterica to inject effector proteins directly into the host cell, enabling the pathogen to manipulate host cell functions for its benefit. This system plays a critical role in the pathogenesis of diseases caused by Salmonella enterica.

Hosts Infected and Associated Diseases:

Salmonella enterica subsp. enterica is a highly adaptable pathogen capable of infecting a wide range of hosts. Its host spectrum includes humans and various animal species, with a particular affinity for poultry and livestock. This adaptability contributes to its ability to persist and cause infections in diverse ecological niches.

In humans, infection with Salmonella enterica typically leads to salmonellosis, a gastrointestinal illness characterized by symptoms such as diarrhea, fever, abdominal cramps, and vomiting. The severity of the disease can vary from mild to severe, and in some cases, it may require medical intervention. This bacterium is a common cause of foodborne illnesses worldwide, often associated with the consumption of contaminated food or water.

In animals, similar clinical manifestations occur, including diarrhea and fever. Livestock and poultry can serve as reservoirs of this pathogen, posing a concern for food safety, as contaminated animal products can transmit the bacterium to humans.

In conclusion, Salmonella enterica subsp. enterica is a Gram-negative bacterium within the Enterobacteriaceae family, known for its complex genome with various genes and proteins contributing to its pathogenicity. It infects a broad range of hosts, including humans and animals, causing diseases such as salmonellosis. Understanding its classification and the genetic factors underpinning its pathogenicity is crucial for managing and preventing infections caused by this versatile pathogen.

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