Diagnostic cardiac troponin I (cTnI) antibodies (anti- cardiac troponin I, anti-cTnI) and diagnostic recombinant cardiac troponin I (cTnI) ) antigens (recombinant cardiac troponin I (cTnI) protein) for Cardiovascular Disease cTnI detection in ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
Catalog Number: GMP-cTnI-Ag;GMP-cTnI-Ab-1;GMP-cTnI-Ab-2
Cardiac troponin I, often denoted as cTnI, is presented in cardiac muscle tissue by a single isoform with a molecular weight of 23.9 kDa. It consists of 209 amino acid residues. The theoretical pI of cTnI is 9.05.cTnI differs from other troponins due to its N-terminal extension of 26 amino acids. This extension contains two serines, residues 23 and 24, which are phosphorylated by protein kinase A in response to beta-adrenergic stimulation and important in increasing the inotropic response.
Phosphorylation of cTnI changes the conformation of the protein and modifies its interaction with other troponins as well as the interaction with anti-TnI antibodies. These changes alter the myofilament response to calcium, and are of interest in targeting heart failure. Multiple reaction monitoring of human cTnI has revealed that there are 14 phosphorylation sites and the pattern of phosphorylation observed these sites is changed in response to disease.cTnI has been shown to be phosphorylated by protein kinase A, protein kinase C, protein kinase G, and p21-activated kinase 3.
A significant part of cTnI released into the patient's blood stream is phosphorylated. For more than 15 years cTnI has been known as a reliable marker of cardiac muscle tissue injury. It is considered to be more sensitive and significantly more specific in diagnosis of the myocardial infarction than the "golden marker" of last decades – CK-MB, as well as total creatine kinase, myoglobin and lactate dehydrogenase isoenzymes.
Genemedi produces core diagnostic ingredients for test of Cardiovascular Disease and related syndrome.
GeneMedi offers paired diagnostics grade cardiac troponin I (cTnI) ) antibodies (monoclonal antibody, mab) and cardiac troponin I (cTnI) ) antigens for Cardiovascular Disease rapid test kit of cardiac troponin I (cTnI) ) testing in ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
All the antibodies and antigens for Cardiovascular Disease test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody.The antigens can be used for antibodies rapid test of Cardiovascular Disease.
Order information
Catalog No. | Size | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-cTnI-Ag | Size:1mg | 3090 | ||
GMP-cTnI-Ag | Size:10mg | 21890 | ||
GMP-cTnI-Ag | Size:100mg | 148000 | ||
GMP-cTnI-Ab-1 | Size:1mg | 1953 | ||
GMP-cTnI-Ab-1 | Size:10mg | 13671 | ||
GMP-cTnI-Ab-1 | Size:100mg | 95697 | ||
GMP-cTnI-Ab-2 | Size:1mg | 1953 | ||
GMP-cTnI-Ab-2 | Size:10mg | 13671 | ||
GMP-cTnI-Ab-2 | Size:100mg | 95697 | ||
GMP-cTnI-Ag/Ab-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Cat No. | GMP-cTnI-Ag |
Product Name | Recombinant Cardiac troponin I (cTnI, His Tag) |
Expression platform | E.coli |
Isotypes | Recombinant Antigen |
Bioactivity validation | Cardiac troponin I (cTnI) Antibody Binding, Immunogen in Sandwich ELISA test, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT |
Tag | His |
Products description | Recombinant Cardiac troponin I (cTnI, His Tag) is produced by E.coli expression system with a 6His tag. |
Specics | NA |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-cTnI-Ab-1; GMP-cTnI-Ab-2 |
Product Name | Anti-cardiac troponin I (cTnI) mouse monoclonal antibody(mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody pair. |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Human cardiac troponin I (cTnI) protein binding, ELISA validated as capture antibody and detection antibody. Pair in cTnIlevel test and Cardiovascular Disease evaluation. |
Tag | mFc |
Products description | Anti-cardiac troponin I (cTnI) mouse monoclonal antibody(mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody pair. |
Specics | mouse |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Diagnostic antibodies and antigens for Heart disease & Cardiovascular disease biomarkers testing
Cat No. | Antibody/Antigen Name | Source (Expression Host) | Isotypes | Bioactivity validation | Order |
GMP-h-MPO-Ag01 | Recombinant human Myeloperoxidase (MPO) Protein | E.coli | Recombinant Antigen | Myeloperoxidase (MPO) Antibody Binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in MPO level test for inflammation test and heart failure diagnosis. | |
GMP-h-MPO-Ab01 | Anti-human Myeloperoxidase (MPO) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-MPO-Ab02,GMP-h-MPO-Ab03 in Myeloperoxidase (MPO) biomarker test for inflammation test and heart failure diagnosis. | |
GMP-h-MPO-Ab02 | Anti-human Myeloperoxidase (MPO) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-MPO-Ab01,GMP-h-MPO-Ab03 in Myeloperoxidase (MPO) biomarker test for inflammation test and heart failure diagnosis. | |
GMP-h-MPO-Ab03 | Anti-human Myeloperoxidase (MPO) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-MPO-Ab01,GMP-h-MPO-Ab02 in Myeloperoxidase (MPO) biomarker test for inflammation test and heart failure diagnosis. | |
GMP-h-MMP-3-Ag01 | Recombinant human matrix metalloproteinase-3 (MMP3) Protein | E.coli | Recombinant Antigen | matrix metalloproteinase-3 (MMP3) Antibody Binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as ontrol material in MMP3 level test for inflammation test and heart failure diagnosis. | |
GMP-h-MMP-3-Ab01 | Anti-human matrix metalloproteinase-3 (MMP3) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-MMP-3-Ab02,GMP-h-MMP-3-Ab03 in matrix metalloproteinase-3 (MMP3) biomarker test for inflammation test and heart failure diagnosis. | |
GMP-h-MMP-3-Ab02 | Anti-human matrix metalloproteinase-3 (MMP3) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-MMP-3-Ab01,GMP-h-MMP-3-Ab03 in matrix metalloproteinase-3 (MMP3) biomarker test for inflammation test and heart failure diagnosis. | |
GMP-h-MMP-3-Ab03 | Anti-human matrix metalloproteinase-3 (MMP3) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-MMP-3-Ab01,GMP-h-MMP-3-Ab02 in matrix metalloproteinase-3 (MMP3) biomarker test for inflammation test and heart failure diagnosis. | |
GMP-h-GDF-15-Ag01 | Recombinant human Growth differentiation factor-15 (GDF-15) Protein | E.coli | Recombinant Antigen | Growth differentiation factor-15 (GDF-15) Antibody Binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in GDF-15 level test for heart failure, cardiovascular diseases,diabetes diagnosis and mitochondrial disorder disease test. | |
GMP-h-GDF-15-Ab01 | Anti-human Growth differentiation factor-15 (GDF-15) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-GDF-15-Ab02,GMP-h-GDF-15-Ab03 in Growth differentiation factor-15 (GDF-15) biomarker test for heart failure, cardiovascular diseases,diabetes diagnosis and mitochondrial disorder disease test. | |
GMP-h-GDF-15-Ab02 | Anti-human Growth differentiation factor-15 (GDF-15) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-GDF-15-Ab01,GMP-h-GDF-15-Ab03 in Growth differentiation factor-15 (GDF-15) biomarker test for heart failure diagnosis and mitochondrial disorder disease test. | |
GMP-h-GDF-15-Ab03 | Anti-human Growth differentiation factor-15 (GDF-15) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-GDF-15-Ab01,GMP-h-GDF-15-Ab02 in Growth differentiation factor-15 (GDF-15) biomarker test for heart failure, cardiovascular diseases,diabetes diagnosis and mitochondrial disorder disease test. | |
GMP-h-CK-MB-Ag01 | Recombinant human Creatine Kinase MB (CK-MB) Protein | E.coli | Recombinant Antigen | Creatine Kinase MB (CK-MB) Antibody Binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in CK-MB( (creatine kinase myocardial band)) level test for acute myocardial infarction test and heart failure diagnosis. | |
GMP-h-CK-MB-Ab01 | Anti-human Creatine Kinase MB (CK-MB) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-CK-MB-Ab02,GMP-GMP-h-CK-MB-Ab03,GMP-h-CK-MB-Ab04 in Creatine Kinase MB (CK-MB) cardiac biomarker test for acute myocardial infarction test and heart failure diagnosis. | |
GMP-h-CK-MB-Ab02 | Anti-human Creatine Kinase MB (CK-MB) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-CK-MB-Ab01,GMP-GMP-h-CK-MB-Ab03,GMP-h-CK-MB-Ab04 in Creatine Kinase MB (CK-MB) cardiac biomarker test for acute myocardial infarction test and heart failure diagnosis. | |
GMP-h-CK-MB-Ab03 | Anti-human Creatine Kinase MB (CK-MB) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-CK-MB-Ab01,GMP-GMP-h-CK-MB-Ab02,GMP-h-CK-MB-Ab04 in Creatine Kinase MB (CK-MB) cardiac biomarker test for acute myocardial infarction test and heart failure diagnosis. | |
GMP-h-CK-MB-Ab04 | Anti-human Creatine Kinase MB (CK-MB) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-CK-MB-Ab01,GMP-GMP-h-CK-MB-Ab02,GMP-h-CK-MB-Ab03 in Creatine Kinase MB (CK-MB) cardiac biomarker test for acute myocardial infarction test and heart failure diagnosis. | |
GMP-h-Myo-Ag01 | Recombinant human Myoglobin (Myo) Protein | E.coli | Recombinant Antigen | Myoglobin (Myo) Antibody Binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in Myoglobin (Myo) level test for heart muscle damage test and heart failure diagnosis. | |
GMP-h-Myo-Ab01 | Anti-human Myoglobin (Myo) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-Myo-Ab02,GMP-h-Myo-Ab03,GMP-h-Myo-Ab04 in Myoglobin (Myo) cardiac biomarker test for heart muscle damage test and heart failure diagnosis. | |
GMP-h-Myo-Ab02 | Anti-human Myoglobin (Myo) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-Myo-Ab01,GMP-h-Myo-Ab03,GMP-h-Myo-Ab04 in Myoglobin (Myo) cardiac biomarker test for heart muscle damage test and heart failure diagnosis. | |
GMP-h-Myo-Ab03 | Anti-human Myoglobin (Myo) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-Myo-Ab01,GMP-h-Myo-Ab02,GMP-h-Myo-Ab04 in Myoglobin (Myo) cardiac biomarker test for heart muscle damage test and heart failure diagnosis. | |
GMP-h-Myo-Ab04 | Anti-human Myoglobin (Myo) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody Pair recommendation with GMP-h-Myo-Ab01,GMP-h-Myo-Ab02,GMP-h-Myo-Ab03 in Myoglobin (Myo) cardiac biomarker test for heart muscle damage test and heart failure diagnosis. | |
GMP-h-Soluble ST2-Ag01 | Recombinant human soluble ST2 (sST2) Protein | E.coli | Recombinant Antigen | Soluble ST2 (sST2) Antibody Binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in soluble ST2 (sST2) level test for heart failure diagnosis, myocardial wall stress and activation of cardiac fibrosis. | |
GMP-h-Soluble ST2-Ab01 | Anti-human human soluble ST2 (sST2) mouse monoclonal antibody(mAb) | Hybridoma | Mouse IgG | ELISA validated as capture antibody and detection antibody in soluble ST2 (sST2) cardiac biomarker test for heart failure diagnosis, myocardial wall stress and activation of cardiac fibrosis. |
Diagnostic antibodies and antigens for Heart disease & Cardiovascular disease biomarkers testing
Genemedi supplies antibodies and antigens for Heart disease & Cardiovascular disease biomarkers testing for a wide selection of choices (please see below).
MPO
MMP-3
GDF-15
CK-MB
Myo
Soluble ST2
cTnT
NT-proBNP
Dig
H-FABP
ApoA
ApoE
BNP
D-Dimer
cTnI
proBNP
SAH
HCY
Digoxin
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