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human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-X-C motif) receptor 6(CXCR6) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to CXCR6/CXCR6 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-X-C motif) receptor 6 (CXCR6) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
C-X-C chemokine receptor type 6 is a protein that in humans is encoded by the CXCR6 gene. CXCR6 has also recently been designated CD186 (cluster of differentiation 186).
CXCR6 has been identified as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. It is a minor coreceptor for HIV-1, nearly all strains of which use CCR5 and/or CXCR4. Most SIV strains can use CXCR6 and recent evidence suggests that in monkeys that serve as the natural hosts of SIV, CXCR6 may be a major coreceptor. CXCR6 was previously known as "Bonzo" and "STRL33" in the HIV/SIV field.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T53975-Ag-1 | chemokine (C-X-C motif) receptor 6 (CXCR6) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T53975-Ab-1 | Anti-CXCR6 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T53975-Ab-2 | Anti-CXCR6 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T53975-Ag-1 | chemokine (C-X-C motif) receptor 6 (CXCR6) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T53975-Ab-1 | Anti-CXCR6 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T53975-Ab-2 | Anti-CXCR6 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T53975-Ag-1 | chemokine (C-X-C motif) receptor 6 (CXCR6) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T53975-Ab-1 | Anti-CXCR6 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T53975-Ab-2 | Anti-CXCR6 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T53975-Ag-1 | chemokine (C-X-C motif) receptor 6 (CXCR6) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T53975-Ab-1 | Anti-CXCR6 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T53975-Ab-2 | Anti-CXCR6 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | CXCR6 |
| Full name | chemokine (C-X-C motif) receptor 6 |
| Gene ID | 10663 |
| Gene Name | CXCR6 |
| Gene Alias | BONZO, CD186, STRL33, TYMSTR |
| Protein Sub-location | Transmembrane Protein |
Antigen Information
| Cat No. | GM-Tg-hg-T53975-Ag-1, GM-Tg-rg-T53975-Ag-1, GM-Tg-mg-T53975-Ag-1, GM-Tg-cynog-T53975-Ag-1 |
| Products Name | chemokine (C-X-C motif) receptor 6 (CXCR6) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-X-C motif) receptor 6 (CXCR6) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T53975-Ab-1, GM-Tg-hg-T53975-Ab-2, GM-Tg-rg-T53975-Ab-1, GM-Tg-rg-T53975-Ab-2, GM-Tg-mg-T53975-Ab-1, GM-Tg-mg-T53975-Ab-2, GM-Tg-cynog-T53975-Ab-1, GM-Tg-cynog-T53975-Ab-2 |
| Products Name | Anti-CXCR6 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CXCR6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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