Human CASR/CAR/ EIG8 ORF/cDNA clone-Lentivirus plasmid (NM_001178065)
Pre-made Human CASR/CAR/ EIG8 Lentiviral expression plasmid for CASR lentivirus packaging, CASR lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.
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Product information
Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
---|---|---|---|
pGMLV000369 | Human CASR Lentivirus plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
High Quality (HQ) Grade | |||
Seed | 5ug |
Product Description
Catalog ID | pGMLV000369 |
Gene Name | CASR |
Accession Number | NM_001178065 |
Gene ID | 846 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 3267 bp |
Gene Alias | CAR, EIG8, FHH, FIH, GPRC2A, HHC, HHC1, HYPOC1, NSHPT, PCAR1, hCasR |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocinmyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T92076-Ab | Anti-CASR/ CAR/ EIG8 monoclonal antibody |
Target Antigen | GM-Tg-g-T92076-Ag | CASR VLP (virus-like particle) |
ORF Viral Vector | pGMLV000369 | Human CASR Lentivirus plasmid |
ORF Viral Vector | pGMLV001246 | Human CASR Lentivirus plasmid |
ORF Viral Vector | vGMLV000369 | Human CASR Lentivirus particle |
ORF Viral Vector | vGMLV001246 | Human CASR Lentivirus particle |
Target information
Target ID | GM-T92076 |
Target Name | CASR |
Gene ID | 846, 12374, 714441, 24247, 100302732, 488007, 281038, 100034084 |
Gene Symbol and Synonyms | BoPCaR1,CAR,CASR,EIG8,FHH,FIH,GPRC2A,hCasR,HHC,HHC1,HYPOC1,NSHPT,PCAR1,RaKCaR |
Uniprot Accession | P41180 |
Uniprot Entry Name | CASR_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000036828 |
Target Classification | Tumor-associated antigen (TAA) |
The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. [provided by RefSeq, Aug 2017]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.