Human FOSL1/FRA/fra-1 ORF/cDNA clone-Lentivirus plasmid (NM_005438.5)

Cat. No.: pGMLV001888
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human FOSL1/FRA/fra-1 Lentiviral expression plasmid for FOSL1 lentivirus packaging, FOSL1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLV001888
Gene Name FOSL1
Accession Number NM_005438.5
Gene ID 8061
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 816 bp
Gene Alias FRA,fra-1,FRA1
Fluorescent Reporter Null
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTTCCGAGACTTCGGGGAACCCGGCCCGAGCTCCGGGAACGGCGGCGGGTACGGCGGCCCCGCGCAGCCCCCGGCCGCAGCGCAGGCAGCCCAGCAGAAGTTCCACCTGGTGCCAAGCATCAACACCATGAGTGGCAGTCAGGAGCTGCAGTGGATGGTACAGCCTCATTTCCTGGGGCCCAGCAGTTACCCCAGGCCTCTGACCTACCCTCAGTACAGCCCCCCACAACCCCGGCCAGGAGTCATCCGGGCCCTGGGGCCGCCTCCAGGGGTACGTCGAAGGCCTTGTGAACAGATCAGCCCGGAGGAAGAGGAGCGCCGCCGAGTAAGGCGCGAGCGGAACAAGCTGGCTGCGGCCAAGTGCAGGAACCGGAGGAAGGAACTGACCGACTTCCTGCAGGCGGAGACTGACAAACTGGAAGATGAGAAATCTGGGCTGCAGCGAGAGATTGAGGAGCTGCAGAAGCAGAAGGAGCGCCTAGAGCTGGTGCTGGAAGCCCACCGACCCATCTGCAAAATCCCGGAAGGAGCCAAGGAGGGGGACACAGGCAGTACCAGTGGCACCAGCAGCCCACCAGCCCCCTGCCGCCCTGTACCTTGTATCTCCCTTTCCCCAGGGCCTGTGCTTGAACCTGAGGCACTGCACACCCCCACACTCATGACCACACCCTCCCTAACTCCTTTCACCCCCAGCCTGGTCTTCACCTACCCCAGCACTCCTGAGCCTTGTGCCTCAGCTCATCGCAAGAGTAGCAGCAGCAGCGGAGACCCATCCTCTGACCCCCTTGGCTCTCCAACCCTCCTCGCTTTGTGA
ORF Protein Sequence MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLGPSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKEGDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPSTPEPCASAHRKSSSSSGDPSSDPLGSPTLLAL

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T89299-Ab Anti-FOSL1 monoclonal antibody
    Target Antigen GM-Tg-g-T89299-Ag FOSL1 protein
    ORF Viral Vector pGMLP002676 Human FOSL1 Lentivirus plasmid
    ORF Viral Vector pGMLV001888 Human FOSL1 Lentivirus plasmid
    ORF Viral Vector pGMLV002226 Human FOSL1 Lentivirus plasmid
    ORF Viral Vector pGMAD001391 Human FOSL1 Adenovirus plasmid
    ORF Viral Vector vGMLP002676 Human FOSL1 Lentivirus particle
    ORF Viral Vector vGMLV001888 Human FOSL1 Lentivirus particle
    ORF Viral Vector vGMLV002226 Human FOSL1 Lentivirus particle
    ORF Viral Vector vGMAD001391 Human FOSL1 Adenovirus particle


    Target information

    Target ID GM-T89299
    Target Name FOSL1
    Gene ID 8061, 14283, 106993191, 25445, 101101337, 483724, 531389, 100051930
    Gene Symbol and Synonyms FOSL1,FRA,fra-1,FRA1
    Uniprot Accession P15407
    Uniprot Entry Name FOSL1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000175592
    Target Classification Tumor-associated antigen (TAA)

    The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]



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