Human SIM2/bHLHe15/HMC13F06 ORF/cDNA clone-Lentivirus particle (NM_009586)

Cat. No.: vGMLP003215

Pre-made Human SIM2/bHLHe15/HMC13F06 Lentiviral expression plasmid for SIM2 lentivirus packaging, SIM2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Target products collection

Go to SIM-2/SIM2/bHLHe15 products collection>>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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pdf Datasheet

Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP003215 Human SIM2 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP003215
Gene Name SIM2
Accession Number NM_009586
Gene ID 6493
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 1713 bp
Gene Alias bHLHe15,HMC13F06,HMC29C01,SIM
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAAGGAGAAGTCCAAGAATGCGGCCAAGACCAGGAGGGAGAAGGAAAATGGCGAGTTTTACGAGCTTGCCAAGCTGCTCCCGCTGCCGTCGGCCATCACTTCGCAGCTGGACAAAGCGTCCATCATCCGCCTCACCACGAGCTACCTGAAGATGCGCGCCGTCTTCCCCGAAGGTTTAGGAGACGCGTGGGGACAGCCGAGCCGCGCCGGGCCCCTGGACGGCGTCGCCAAGGAGCTGGGATCGCACTTGCTGCAGACTTTGGATGGATTTGTTTTTGTGGTAGCATCTGATGGCAAAATCATGTATATATCCGAGACCGCTTCTGTCCATTTAGGCTTATCCCAGGTGGAGCTCACGGGCAACAGTATTTATGAATACATCCATCCTTCTGACCACGATGAGATGACCGCTGTCCTCACGGCCCACCAGCCGCTGCACCACCACCTGCTCCAAGAGTATGAGATAGAGAGGTCGTTCTTTCTTCGAATGAAATGTGTCTTGGCGAAAAGGAACGCGGGCCTGACCTGCAGCGGATACAAGGTCATCCACTGCAGTGGCTACTTGAAGATCAGGCAGTATATGCTGGACATGTCCCTGTACGACTCCTGCTACCAGATTGTGGGGCTGGTGGCCGTGGGCCAGTCGCTGCCACCCAGTGCCATCACCGAGATCAAGCTGTACAGTAACATGTTCATGTTCAGGGCCAGCCTTGACCTGAAGCTGATATTCCTGGATTCCAGGGTGACCGAGGTGACGGGGTACGAGCCGCAGGACCTGATCGAGAAGACCCTATACCATCACGTGCACGGCTGCGACGTGTTCCACCTCCGCTACGCACACCACCTCCTGTTGGTGAAGGGCCAGGTCACCACCAAGTACTACCGGCTGCTGTCCAAGCGGGGCGGCTGGGTGTGGGTGCAGAGCTACGCCACCGTGGTGCACAACAGCCGCTCGTCCCGGCCCCACTGCATCGTGAGTGTCAATTATGTACTCACGGAGATTGAATACAAGGAACTTCAGCTGTCCCTGGAGCAGGTGTCCACTGCCAAGTCCCAGGACTCCTGGAGGACCGCCTTGTCTACCTCACAAGAAACTAGGAAATTAGTGAAACCCAAAAATACCAAGATGAAGACAAAGCTGAGAACAAACCCTTACCCCCCACAGCAATACAGCTCGTTCCAAATGGACAAACTGGAATGCGGCCAGCTCGGAAACTGGAGAGCCAGTCCCCCTGCAAGCGCTGCTGCTCCTCCAGAACTGCAGCCCCACTCAGAAAGCAGTGACCTTCTGTACACGCCATCCTACAGCCTGCCCTTCTCCTACCATTACGGACACTTCCCTCTGGACTCTCACGTCTTCAGCAGCAAAAAGCCAATGTTGCCGGCCAAGTTCGGGCAGCCCCAAGGATCCCCTTGTGAGGTGGCACGCTTTTTCCTGAGCACACTGCCAGCCAGCGGTGAATGCCAGTGGCATTATGCCAACCCCCTAGTGCCTAGCAGCTCGTCTCCAGCTAAAAATCCTCCAGAGCCACCGGCGAACACTGCTAGGCACAGCCTGGTGCCAAGCTACGAAGGTGGGTCAGGTCTGCTCGTGGGGAAGGTGGGAGGACTGCGCACGGCCGGGAGCCGAAGCAGCCATGGCGGTGGGTGGCAGATGGAGACAGAACCCTCACGCTTTGGGCAAACTTGCCCTCTTTCTGCTTCTAAGTAG
ORF Protein Sequence MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRAVFPEGLGDAWGQPSRAGPLDGVAKELGSHLLQTLDGFVFVVASDGKIMYISETASVHLGLSQVELTGNSIYEYIHPSDHDEMTAVLTAHQPLHHHLLQEYEIERSFFLRMKCVLAKRNAGLTCSGYKVIHCSGYLKIRQYMLDMSLYDSCYQIVGLVAVGQSLPPSAITEIKLYSNMFMFRASLDLKLIFLDSRVTEVTGYEPQDLIEKTLYHHVHGCDVFHLRYAHHLLLVKGQVTTKYYRLLSKRGGWVWVQSYATVVHNSRSSRPHCIVSVNYVLTEIEYKELQLSLEQVSTAKSQDSWRTALSTSQETRKLVKPKNTKMKTKLRTNPYPPQQYSSFQMDKLECGQLGNWRASPPASAAAPPELQPHSESSDLLYTPSYSLPFSYHYGHFPLDSHVFSSKKPMLPAKFGQPQGSPCEVARFFLSTLPASGECQWHYANPLVPSSSSPAKNPPEPPANTARHSLVPSYEGGSGLLVGKVGGLRTAGSRSSHGGGWQMETEPSRFGQTCPLSASK

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IO131-Ab Anti-SIM-2 monoclonal antibody
    Target Antigen GM-Tg-g-IO131-Ag SIM-2/SIM2 protein
    ORF Viral Vector pGMLP003215 Human SIM2 Lentivirus plasmid
    ORF Viral Vector vGMLP003215 Human SIM2 Lentivirus particle


    Target information

    Target ID GM-IO131
    Target Name SIM-2
    Gene ID 6493, 20465, 697052, 304071, 101101246, 607987, 100337422, 100061169
    Gene Symbol and Synonyms bHLHe15,HMC13F06,HMC29C01,SIM,SIM2
    Uniprot Accession Q14190
    Uniprot Entry Name SIM2_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease Not Available
    Gene Ensembl ENSG00000159263
    Target Classification Checkpoint-Immuno Oncology

    This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.