Human GADD45A/DDIT1/GADD45 ORF/cDNA clone-Lentivirus particle (NM_001924.4)

Cat. No.: vGMLV001473

Pre-made Human GADD45A/DDIT1/GADD45 Lentiviral expression plasmid for GADD45A lentivirus packaging, GADD45A lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLV001473 Human GADD45A Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLV001473
Gene Name GADD45A
Accession Number NM_001924.4
Gene ID 1647
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 498 bp
Gene Alias DDIT1,GADD45
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGACTTTGGAGGAATTCTCGGCTGGAGAGCAGAAGACCGAAAGGATGGATAAGGTGGGGGATGCCCTGGAGGAAGTGCTCAGCAAAGCCCTGAGTCAGCGCACGATCACTGTCGGGGTGTACGAAGCGGCCAAGCTGCTCAACGTCGACCCCGATAACGTGGTGTTGTGCCTGCTGGCGGCGGACGAGGACGACGACAGAGATGTGGCTCTGCAGATCCACTTCACCCTGATCCAGGCGTTTTGCTGCGAGAACGACATCAACATCCTGCGCGTCAGCAACCCGGGCCGGCTGGCGGAGCTCCTGCTCTTGGAGACCGACGCTGGCCCCGCGGCGAGCGAGGGCGCCGAGCAGCCCCCGGACCTGCACTGCGTGCTGGTGACGAATCCACATTCATCTCAATGGAAGGATCCTGCCTTAAGTCAACTTATTTGTTTTTGCCGGGAAAGTCGCTACATGGATCAATGGGTTCCAGTGATTAATCTCCCTGAACGGTGA
ORF Protein Sequence MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-TA007-Ab Anti-GADD45A monoclonal antibody
    Target Antigen GM-Tg-g-TA007-Ag GADD45A protein
    ORF Viral Vector pGMLV001473 Human GADD45A Lentivirus plasmid
    ORF Viral Vector pGMAP000143 Human GADD45A Adenovirus plasmid
    ORF Viral Vector vGMLV001473 Human GADD45A Lentivirus particle
    ORF Viral Vector vGMAP000143 Human GADD45A Adenovirus particle


    Target information

    Target ID GM-TA007
    Target Name GADD45A
    Gene ID 1647, 13197, 701054, 25112, 493656, 100855728, 505463, 100630299
    Gene Symbol and Synonyms DDIT1,GADD45,GADD45A
    Uniprot Accession P24522
    Uniprot Entry Name GA45A_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Prostate Cancer
    Gene Ensembl ENSG00000116717
    Target Classification Not Available

    This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010]



    About GMVC

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