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Anti-COX7A2 monoclonal antibody
Pre-made anti-COX7A2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to COX7A2/COX7A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0604-Ab-1/ GM-Tg-hg-IP0604-Ab-2 | Anti-Human COX7A2 monoclonal antibody | Human |
| GM-Tg-rg-IP0604-Ab-1/ GM-Tg-rg-IP0604-Ab-2 | Anti-Rat COX7A2 monoclonal antibody | Rat |
| GM-Tg-mg-IP0604-Ab-1/ GM-Tg-mg-IP0604-Ab-2 | Anti-Mouse COX7A2 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0604-Ab-1/ GM-Tg-cynog-IP0604-Ab-2 | Anti-Cynomolgus/ Rhesus macaque COX7A2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0604-Ab-1/ GM-Tg-felg-IP0604-Ab-2 | Anti-Feline COX7A2 monoclonal antibody | Feline |
| GM-Tg-cang-IP0604-Ab-1/ GM-Tg-cang-IP0604-Ab-2 | Anti-Canine COX7A2 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0604-Ab-1/ GM-Tg-bovg-IP0604-Ab-2 | Anti-Bovine COX7A2 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0604-Ab-1/ GM-Tg-equg-IP0604-Ab-2 | Anti-Equine COX7A2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0604-Ab-1/ GM-Tg-hg-IP0604-Ab-2; GM-Tg-rg-IP0604-Ab-1/ GM-Tg-rg-IP0604-Ab-2; GM-Tg-mg-IP0604-Ab-1/ GM-Tg-mg-IP0604-Ab-2; GM-Tg-cynog-IP0604-Ab-1/ GM-Tg-cynog-IP0604-Ab-2; GM-Tg-felg-IP0604-Ab-1/ GM-Tg-felg-IP0604-Ab-2; GM-Tg-cang-IP0604-Ab-1/ GM-Tg-cang-IP0604-Ab-2; GM-Tg-bovg-IP0604-Ab-1/ GM-Tg-bovg-IP0604-Ab-2; GM-Tg-equg-IP0604-Ab-1/ GM-Tg-equg-IP0604-Ab-2 |
| Products Name | Anti-COX7A2 monoclonal antibody |
| Format | mab |
| Target Name | COX7A2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-COX7A2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0604-Ag-1 | Recombinant multi-species CX7A2/ COX7A2/ COX7AL protein |
| ORF Viral Vector | pGMLP004685 | human Cox7a2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004685 | human Cox7a2 Lentivirus particle |
Target information
| Target ID | GM-IP0604 |
| Target Name | COX7A2 |
| Gene ID | 1347,12866,29507,717879,119863903,101093608,327688,100630209 |
| Gene Symbol and Synonyms | COX7A2,Cox7a3,COX7AL,COX7AL1,COXVIIa-L,COXVIIAL,LOC119863903,LOC717879,VIIAL |
| Uniprot Accession | P14406,P35171,P13184 |
| Uniprot Entry Name | CX7A2_HUMAN,CX7A2_RAT,CX7A2_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000112695 |
| Target Classification | N/A |
The target: COX7A2, gene name: COX7A2, also named as COX7AL, COX7AL1, COXVIIAL, COXVIIa-L, VIIAL. Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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