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Anti-DDRGK1 monoclonal antibody
Pre-made anti-DDRGK1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to DDRGK1/DDRGK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0675-Ab-1/ GM-Tg-hg-IP0675-Ab-2 | Anti-Human DDRGK1 monoclonal antibody | Human |
| GM-Tg-rg-IP0675-Ab-1/ GM-Tg-rg-IP0675-Ab-2 | Anti-Rat DDRGK1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0675-Ab-1/ GM-Tg-mg-IP0675-Ab-2 | Anti-Mouse DDRGK1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0675-Ab-1/ GM-Tg-cynog-IP0675-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DDRGK1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0675-Ab-1/ GM-Tg-felg-IP0675-Ab-2 | Anti-Feline DDRGK1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0675-Ab-1/ GM-Tg-cang-IP0675-Ab-2 | Anti-Canine DDRGK1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0675-Ab-1/ GM-Tg-bovg-IP0675-Ab-2 | Anti-Bovine DDRGK1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0675-Ab-1/ GM-Tg-equg-IP0675-Ab-2 | Anti-Equine DDRGK1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0675-Ab-1/ GM-Tg-hg-IP0675-Ab-2; GM-Tg-rg-IP0675-Ab-1/ GM-Tg-rg-IP0675-Ab-2; GM-Tg-mg-IP0675-Ab-1/ GM-Tg-mg-IP0675-Ab-2; GM-Tg-cynog-IP0675-Ab-1/ GM-Tg-cynog-IP0675-Ab-2; GM-Tg-felg-IP0675-Ab-1/ GM-Tg-felg-IP0675-Ab-2; GM-Tg-cang-IP0675-Ab-1/ GM-Tg-cang-IP0675-Ab-2; GM-Tg-bovg-IP0675-Ab-1/ GM-Tg-bovg-IP0675-Ab-2; GM-Tg-equg-IP0675-Ab-1/ GM-Tg-equg-IP0675-Ab-2 |
| Products Name | Anti-DDRGK1 monoclonal antibody |
| Format | mab |
| Target Name | DDRGK1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-DDRGK1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0675-Ag-1 | Recombinant multi-species DDRGK/ DDRGK1/ C20orf116 protein |
| ORF Viral Vector | pGMLP003177 | human DDRGK1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003177 | human DDRGK1 Lentivirus particle |
| ORF Viral Vector | pGMAAV000194 | house mouse Ddrgk1 AAV plasmid |
| ORF Viral Vector | pGMLPm000593 | mouse Ddrgk1 Lentivirus plasmid |
| ORF Viral Vector | vGMAAV000194 | house mouse Ddrgk1 AAV particle |
| ORF Viral Vector | vGMLPm000593 | mouse Ddrgk1 Lentivirus particle |
Target information
| Target ID | GM-IP0675 |
| Target Name | DDRGK1 |
| Gene ID | 65992,77006,296162,717226,477173,101094750,511144,100066678 |
| Gene Symbol and Synonyms | 1110001I20Rik,2600009E05Rik,C13H20ORF116,C20orf116,DDRGK1,dJ1187M17.3,RGD1309979,SEMDSH,UFBP1 |
| Uniprot Accession | Q96HY6,Q1LZB0 |
| Uniprot Entry Name | DDRGK_HUMAN,DDRGK_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000198171 |
| Target Classification | N/A |
The target: DDRGK1, gene name: DDRGK1, also named as C20orf116, SEMDSH, UFBP1, dJ1187M17.3. The protein encoded by this gene interacts with components of the ubiquitin fold modifier 1 conjugation pathway and helps prevent apoptosis in ER-stressed secretory tissues. In addition, the encoded protein regulates nuclear factor-κB activity. [provided by RefSeq, Dec 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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