Anti-DNAJC15 monoclonal antibody

Pre-made anti-DNAJC15 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to DNAJC15/DNAJC15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0707-Ab-1/ GM-Tg-hg-IP0707-Ab-2Anti-Human DNAJC15 monoclonal antibodyHuman
GM-Tg-rg-IP0707-Ab-1/ GM-Tg-rg-IP0707-Ab-2Anti-Rat DNAJC15 monoclonal antibodyRat
GM-Tg-mg-IP0707-Ab-1/ GM-Tg-mg-IP0707-Ab-2Anti-Mouse DNAJC15 monoclonal antibodyMouse
GM-Tg-cynog-IP0707-Ab-1/ GM-Tg-cynog-IP0707-Ab-2Anti-Cynomolgus/ Rhesus macaque DNAJC15 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0707-Ab-1/ GM-Tg-felg-IP0707-Ab-2Anti-Feline DNAJC15 monoclonal antibodyFeline
GM-Tg-cang-IP0707-Ab-1/ GM-Tg-cang-IP0707-Ab-2Anti-Canine DNAJC15 monoclonal antibodyCanine
GM-Tg-bovg-IP0707-Ab-1/ GM-Tg-bovg-IP0707-Ab-2Anti-Bovine DNAJC15 monoclonal antibodyBovine
GM-Tg-equg-IP0707-Ab-1/ GM-Tg-equg-IP0707-Ab-2Anti-Equine DNAJC15 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0707-Ab-1/ GM-Tg-hg-IP0707-Ab-2; GM-Tg-rg-IP0707-Ab-1/ GM-Tg-rg-IP0707-Ab-2;
GM-Tg-mg-IP0707-Ab-1/ GM-Tg-mg-IP0707-Ab-2; GM-Tg-cynog-IP0707-Ab-1/ GM-Tg-cynog-IP0707-Ab-2;
GM-Tg-felg-IP0707-Ab-1/ GM-Tg-felg-IP0707-Ab-2; GM-Tg-cang-IP0707-Ab-1/ GM-Tg-cang-IP0707-Ab-2;
GM-Tg-bovg-IP0707-Ab-1/ GM-Tg-bovg-IP0707-Ab-2; GM-Tg-equg-IP0707-Ab-1/ GM-Tg-equg-IP0707-Ab-2
Products NameAnti-DNAJC15 monoclonal antibody
Formatmab
Target NameDNAJC15
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-DNAJC15 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0707-Ag-1Recombinant multi-species DJC15/ DNAJC15/ DNAJD1 protein
    ORF Viral VectorvGMLP003407human DNAJC15 Lentivirus particle
    ORF Viral VectorpGMLP003407human DNAJC15 Lentivirus plasmid
    ORF Viral VectorpGMLPm001555mouse Dnajc15 Lentivirus plasmid
    ORF Viral VectorvGMLPm001555mouse Dnajc15 Lentivirus particle


    Target information

    Target IDGM-IP0707
    Target NameDNAJC15
    Gene ID29103,66148,290370,700339,476930,101087037,618047,100051263
    Gene Symbol and Synonyms1110003P16Rik,DNAJC15,DNAJD1,HSD18,MCJ
    Uniprot AccessionQ9Y5T4
    Uniprot Entry NameDJC15_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000120675
    Target ClassificationN/A

    The target: DNAJC15, gene name: DNAJC15, also named as DNAJD1, HSD18, MCJ. Predicted to enable ATPase activator activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to act upstream of or within several processes, including cellular response to starvation; negative regulation of mitochondrial electron transport, NADH to ubiquinone; and negative regulation of protein-containing complex assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be part of PAM complex, Tim23 associated import motor. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.