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Anti-ELOVL5 monoclonal antibody
Pre-made anti-ELOVL5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to ELOVL5/ELOVL5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0749-Ab-1/ GM-Tg-hg-IP0749-Ab-2 | Anti-Human ELOVL5 monoclonal antibody | Human |
| GM-Tg-rg-IP0749-Ab-1/ GM-Tg-rg-IP0749-Ab-2 | Anti-Rat ELOVL5 monoclonal antibody | Rat |
| GM-Tg-mg-IP0749-Ab-1/ GM-Tg-mg-IP0749-Ab-2 | Anti-Mouse ELOVL5 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0749-Ab-1/ GM-Tg-cynog-IP0749-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ELOVL5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0749-Ab-1/ GM-Tg-felg-IP0749-Ab-2 | Anti-Feline ELOVL5 monoclonal antibody | Feline |
| GM-Tg-cang-IP0749-Ab-1/ GM-Tg-cang-IP0749-Ab-2 | Anti-Canine ELOVL5 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0749-Ab-1/ GM-Tg-bovg-IP0749-Ab-2 | Anti-Bovine ELOVL5 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0749-Ab-1/ GM-Tg-equg-IP0749-Ab-2 | Anti-Equine ELOVL5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0749-Ab-1/ GM-Tg-hg-IP0749-Ab-2; GM-Tg-rg-IP0749-Ab-1/ GM-Tg-rg-IP0749-Ab-2; GM-Tg-mg-IP0749-Ab-1/ GM-Tg-mg-IP0749-Ab-2; GM-Tg-cynog-IP0749-Ab-1/ GM-Tg-cynog-IP0749-Ab-2; GM-Tg-felg-IP0749-Ab-1/ GM-Tg-felg-IP0749-Ab-2; GM-Tg-cang-IP0749-Ab-1/ GM-Tg-cang-IP0749-Ab-2; GM-Tg-bovg-IP0749-Ab-1/ GM-Tg-bovg-IP0749-Ab-2; GM-Tg-equg-IP0749-Ab-1/ GM-Tg-equg-IP0749-Ab-2 |
| Products Name | Anti-ELOVL5 monoclonal antibody |
| Format | mab |
| Target Name | ELOVL5 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-ELOVL5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0749-Ag-1 | Recombinant multi-species ELOV5/ ELOVL5/ HELO1 protein |
| ORF Viral Vector | pGMLP003237 | human ELOVL5 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003237 | human ELOVL5 Lentivirus particle |
| ORF Viral Vector | pGMLPm001076 | mouse Elovl5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001076 | mouse Elovl5 Lentivirus particle |
Target information
| Target ID | GM-IP0749 |
| Target Name | ELOVL5 |
| Gene ID | 60481,68801,171400,712243,610377,101086147,617293,100069400 |
| Gene Symbol and Synonyms | 1110059L23Rik,dJ483K16.1,ELOVL5,HELO1,rELO1,SCA38 |
| Uniprot Accession | Q9NYP7,Q920L7,Q2KJD9 |
| Uniprot Entry Name | ELOV5_HUMAN,ELOV5_RAT,ELOV5_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000012660 |
| Target Classification | N/A |
The target: ELOVL5, gene name: ELOVL5, also named as HELO1, SCA38, dJ483K16.1. This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
