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Anti-FIS1 monoclonal antibody
Pre-made anti-FIS1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to FIS1/FIS1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0847-Ab-1/ GM-Tg-hg-IP0847-Ab-2 | Anti-Human FIS1 monoclonal antibody | Human |
| GM-Tg-rg-IP0847-Ab-1/ GM-Tg-rg-IP0847-Ab-2 | Anti-Rat FIS1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0847-Ab-1/ GM-Tg-mg-IP0847-Ab-2 | Anti-Mouse FIS1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0847-Ab-1/ GM-Tg-cynog-IP0847-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FIS1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0847-Ab-1/ GM-Tg-felg-IP0847-Ab-2 | Anti-Feline FIS1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0847-Ab-1/ GM-Tg-cang-IP0847-Ab-2 | Anti-Canine FIS1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0847-Ab-1/ GM-Tg-bovg-IP0847-Ab-2 | Anti-Bovine FIS1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0847-Ab-1/ GM-Tg-equg-IP0847-Ab-2 | Anti-Equine FIS1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0847-Ab-1/ GM-Tg-hg-IP0847-Ab-2; GM-Tg-rg-IP0847-Ab-1/ GM-Tg-rg-IP0847-Ab-2; GM-Tg-mg-IP0847-Ab-1/ GM-Tg-mg-IP0847-Ab-2; GM-Tg-cynog-IP0847-Ab-1/ GM-Tg-cynog-IP0847-Ab-2; GM-Tg-felg-IP0847-Ab-1/ GM-Tg-felg-IP0847-Ab-2; GM-Tg-cang-IP0847-Ab-1/ GM-Tg-cang-IP0847-Ab-2; GM-Tg-bovg-IP0847-Ab-1/ GM-Tg-bovg-IP0847-Ab-2; GM-Tg-equg-IP0847-Ab-1/ GM-Tg-equg-IP0847-Ab-2 |
| Products Name | Anti-FIS1 monoclonal antibody |
| Format | mab |
| Target Name | FIS1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-FIS1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0847-Ag-1 | Recombinant multi-species FIS1/ CGI-135/ TTC11 protein |
| ORF Viral Vector | vGMAD000275 | human FIS1 Adenovirus particle |
| ORF Viral Vector | vGMLP002675 | human FIS1 Lentivirus particle |
| ORF Viral Vector | pGMAD000275 | human FIS1 Adenovirus plasmid |
| ORF Viral Vector | pGMLP002675 | human FIS1 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000048 | rat Fis1 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000048 | rat Fis1 Adenovirus particle |
Target information
| Target ID | GM-IP0847 |
| Target Name | FIS1 |
| Gene ID | 51024,66437,288584,714444,479728,101081944,615565,100059592 |
| Gene Symbol and Synonyms | 2010003O14Rik,CGI-135,FIS1,TTC11 |
| Uniprot Accession | Q9Y3D6,P84817,Q3T0I5 |
| Uniprot Entry Name | FIS1_HUMAN,FIS1_RAT,FIS1_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000214253 |
| Target Classification | N/A |
The target: FIS1, gene name: FIS1, also named as CGI-135, TTC11. The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission (James et al., 2003 [PubMed 12783892]).[supplied by OMIM, Mar 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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