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Anti-HOXC11 monoclonal antibody
Pre-made anti-HOXC11 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to HOXC11/HOXC11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0976-Ab-1/ GM-Tg-hg-IP0976-Ab-2 | Anti-Human HOXC11 monoclonal antibody | Human |
| GM-Tg-rg-IP0976-Ab-1/ GM-Tg-rg-IP0976-Ab-2 | Anti-Rat HOXC11 monoclonal antibody | Rat |
| GM-Tg-mg-IP0976-Ab-1/ GM-Tg-mg-IP0976-Ab-2 | Anti-Mouse HOXC11 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0976-Ab-1/ GM-Tg-cynog-IP0976-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HOXC11 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0976-Ab-1/ GM-Tg-felg-IP0976-Ab-2 | Anti-Feline HOXC11 monoclonal antibody | Feline |
| GM-Tg-cang-IP0976-Ab-1/ GM-Tg-cang-IP0976-Ab-2 | Anti-Canine HOXC11 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0976-Ab-1/ GM-Tg-bovg-IP0976-Ab-2 | Anti-Bovine HOXC11 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0976-Ab-1/ GM-Tg-equg-IP0976-Ab-2 | Anti-Equine HOXC11 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0976-Ab-1/ GM-Tg-hg-IP0976-Ab-2; GM-Tg-rg-IP0976-Ab-1/ GM-Tg-rg-IP0976-Ab-2; GM-Tg-mg-IP0976-Ab-1/ GM-Tg-mg-IP0976-Ab-2; GM-Tg-cynog-IP0976-Ab-1/ GM-Tg-cynog-IP0976-Ab-2; GM-Tg-felg-IP0976-Ab-1/ GM-Tg-felg-IP0976-Ab-2; GM-Tg-cang-IP0976-Ab-1/ GM-Tg-cang-IP0976-Ab-2; GM-Tg-bovg-IP0976-Ab-1/ GM-Tg-bovg-IP0976-Ab-2; GM-Tg-equg-IP0976-Ab-1/ GM-Tg-equg-IP0976-Ab-2 |
| Products Name | Anti-HOXC11 monoclonal antibody |
| Format | mab |
| Target Name | HOXC11 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-HOXC11 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0976-Ag-1 | Recombinant multi-species HXC11/ HOXC11/ HOX3H protein |
| ORF Viral Vector | vGMLP005000 | human HOXC11 Lentivirus particle |
| ORF Viral Vector | pGMLP005000 | human HOXC11 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004636 | mouse Hoxc11 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004636 | mouse Hoxc11 Lentivirus particle |
Target information
| Target ID | GM-IP0976 |
| Target Name | HOXC11 |
| Gene ID | 3227,109663,100911859,106992375,100688428,101089530,536141,100062371 |
| Gene Symbol and Synonyms | Hox-3.7,HOX3H,HOXC11,RGD1305450 |
| Uniprot Accession | O43248 |
| Uniprot Entry Name | HXC11_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000123388 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: HOXC11, gene name: HOXC11, also named as HOX3H. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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