Anti-MAL2 monoclonal antibody

Pre-made anti-MAL2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MAL2/MAL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1137-Ab-1/ GM-Tg-hg-IP1137-Ab-2Anti-Human MAL2 monoclonal antibodyHuman
GM-Tg-rg-IP1137-Ab-1/ GM-Tg-rg-IP1137-Ab-2Anti-Rat MAL2 monoclonal antibodyRat
GM-Tg-mg-IP1137-Ab-1/ GM-Tg-mg-IP1137-Ab-2Anti-Mouse MAL2 monoclonal antibodyMouse
GM-Tg-cynog-IP1137-Ab-1/ GM-Tg-cynog-IP1137-Ab-2Anti-Cynomolgus/ Rhesus macaque MAL2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1137-Ab-1/ GM-Tg-felg-IP1137-Ab-2Anti-Feline MAL2 monoclonal antibodyFeline
GM-Tg-cang-IP1137-Ab-1/ GM-Tg-cang-IP1137-Ab-2Anti-Canine MAL2 monoclonal antibodyCanine
GM-Tg-bovg-IP1137-Ab-1/ GM-Tg-bovg-IP1137-Ab-2Anti-Bovine MAL2 monoclonal antibodyBovine
GM-Tg-equg-IP1137-Ab-1/ GM-Tg-equg-IP1137-Ab-2Anti-Equine MAL2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1137-Ab-1/ GM-Tg-hg-IP1137-Ab-2; GM-Tg-rg-IP1137-Ab-1/ GM-Tg-rg-IP1137-Ab-2;
GM-Tg-mg-IP1137-Ab-1/ GM-Tg-mg-IP1137-Ab-2; GM-Tg-cynog-IP1137-Ab-1/ GM-Tg-cynog-IP1137-Ab-2;
GM-Tg-felg-IP1137-Ab-1/ GM-Tg-felg-IP1137-Ab-2; GM-Tg-cang-IP1137-Ab-1/ GM-Tg-cang-IP1137-Ab-2;
GM-Tg-bovg-IP1137-Ab-1/ GM-Tg-bovg-IP1137-Ab-2; GM-Tg-equg-IP1137-Ab-1/ GM-Tg-equg-IP1137-Ab-2
Products NameAnti-MAL2 monoclonal antibody
Formatmab
Target NameMAL2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MAL2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1137-Ag-1Recombinant multi-species MAL2 protein
    ORF Viral VectorpGMLP002369human MAL2 Lentivirus plasmid
    ORF Viral VectorvGMLP002369human MAL2 Lentivirus particle
    ORF Viral VectorpGMLPm001889mouse Mal2 Lentivirus plasmid
    ORF Viral VectorvGMLPm001889mouse Mal2 Lentivirus particle


    Target information

    Target IDGM-IP1137
    Target NameMAL2
    Gene ID114569,105853,362911,705045,608995,101081865,511940,100066039
    Gene Symbol and SynonymsMAL2
    Uniprot AccessionQ969L2,A2VE13
    Uniprot Entry NameMAL2_HUMAN,MAL2_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000147676
    Target ClassificationN/A

    The target: MAL2, gene name: MAL2, also named as . This gene encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of lipid rafts and, in polarized cells, it primarily localizes to endosomal structures beneath the apical membrane. It is required for transcytosis, an intracellular transport pathway used to deliver membrane-bound proteins and exogenous cargos from the basolateral to the apical surface. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.