Anti-MGST3 monoclonal antibody

Pre-made anti-MGST3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MGST3/MGST3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1188-Ab-1/ GM-Tg-hg-IP1188-Ab-2Anti-Human MGST3 monoclonal antibodyHuman
GM-Tg-rg-IP1188-Ab-1/ GM-Tg-rg-IP1188-Ab-2Anti-Rat MGST3 monoclonal antibodyRat
GM-Tg-mg-IP1188-Ab-1/ GM-Tg-mg-IP1188-Ab-2Anti-Mouse MGST3 monoclonal antibodyMouse
GM-Tg-cynog-IP1188-Ab-1/ GM-Tg-cynog-IP1188-Ab-2Anti-Cynomolgus/ Rhesus macaque MGST3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1188-Ab-1/ GM-Tg-felg-IP1188-Ab-2Anti-Feline MGST3 monoclonal antibodyFeline
GM-Tg-cang-IP1188-Ab-1/ GM-Tg-cang-IP1188-Ab-2Anti-Canine MGST3 monoclonal antibodyCanine
GM-Tg-bovg-IP1188-Ab-1/ GM-Tg-bovg-IP1188-Ab-2Anti-Bovine MGST3 monoclonal antibodyBovine
GM-Tg-equg-IP1188-Ab-1/ GM-Tg-equg-IP1188-Ab-2Anti-Equine MGST3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1188-Ab-1/ GM-Tg-hg-IP1188-Ab-2; GM-Tg-rg-IP1188-Ab-1/ GM-Tg-rg-IP1188-Ab-2;
GM-Tg-mg-IP1188-Ab-1/ GM-Tg-mg-IP1188-Ab-2; GM-Tg-cynog-IP1188-Ab-1/ GM-Tg-cynog-IP1188-Ab-2;
GM-Tg-felg-IP1188-Ab-1/ GM-Tg-felg-IP1188-Ab-2; GM-Tg-cang-IP1188-Ab-1/ GM-Tg-cang-IP1188-Ab-2;
GM-Tg-bovg-IP1188-Ab-1/ GM-Tg-bovg-IP1188-Ab-2; GM-Tg-equg-IP1188-Ab-1/ GM-Tg-equg-IP1188-Ab-2
Products NameAnti-MGST3 monoclonal antibody
Formatmab
Target NameMGST3
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MGST3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1188-Ag-1Recombinant multi-species MGST3/ GST-III protein
    ORF Viral VectorpGMLP002545human MGST3 Lentivirus plasmid
    ORF Viral VectorvGMLP002545human MGST3 Lentivirus particle
    ORF Viral VectorpGMLPm002214mouse Mgst3 Lentivirus plasmid
    ORF Viral VectorvGMLPm002214mouse Mgst3 Lentivirus particle


    Target information

    Target IDGM-IP1188
    Target NameMGST3
    Gene ID4259,66447,289197,695275,609050,101080760,507346,100058514
    Gene Symbol and Synonyms2010012L10Rik,2010306B17Rik,2700004G04Rik,GST-III,MGST3
    Uniprot AccessionO14880,Q3T100
    Uniprot Entry NameMGST3_HUMAN,MGST3_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000143198
    Target ClassificationN/A

    The target: MGST3, gene name: MGST3, also named as GST-III. This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.[provided by RefSeq, May 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.