Anti-OPN1LW monoclonal antibody
Pre-made anti-OPN1LW monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP1304-Ab-1/ GM-Tg-hg-IP1304-Ab-2 | Anti-Human OPN1LW monoclonal antibody | Human |
GM-Tg-rg-IP1304-Ab-1/ GM-Tg-rg-IP1304-Ab-2 | Anti-Rat OPN1LW monoclonal antibody | Rat |
GM-Tg-mg-IP1304-Ab-1/ GM-Tg-mg-IP1304-Ab-2 | Anti-Mouse OPN1LW monoclonal antibody | Mouse |
GM-Tg-cynog-IP1304-Ab-1/ GM-Tg-cynog-IP1304-Ab-2 | Anti-Cynomolgus/ Rhesus macaque OPN1LW monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP1304-Ab-1/ GM-Tg-felg-IP1304-Ab-2 | Anti-Feline OPN1LW monoclonal antibody | Feline |
GM-Tg-cang-IP1304-Ab-1/ GM-Tg-cang-IP1304-Ab-2 | Anti-Canine OPN1LW monoclonal antibody | Canine |
GM-Tg-bovg-IP1304-Ab-1/ GM-Tg-bovg-IP1304-Ab-2 | Anti-Bovine OPN1LW monoclonal antibody | Bovine |
GM-Tg-equg-IP1304-Ab-1/ GM-Tg-equg-IP1304-Ab-2 | Anti-Equine OPN1LW monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP1304-Ab-1/ GM-Tg-hg-IP1304-Ab-2; GM-Tg-rg-IP1304-Ab-1/ GM-Tg-rg-IP1304-Ab-2; GM-Tg-mg-IP1304-Ab-1/ GM-Tg-mg-IP1304-Ab-2; GM-Tg-cynog-IP1304-Ab-1/ GM-Tg-cynog-IP1304-Ab-2; GM-Tg-felg-IP1304-Ab-1/ GM-Tg-felg-IP1304-Ab-2; GM-Tg-cang-IP1304-Ab-1/ GM-Tg-cang-IP1304-Ab-2; GM-Tg-bovg-IP1304-Ab-1/ GM-Tg-bovg-IP1304-Ab-2; GM-Tg-equg-IP1304-Ab-1/ GM-Tg-equg-IP1304-Ab-2 |
Products Name | Anti-OPN1LW monoclonal antibody |
Format | mab |
Target Name | OPN1LW |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-OPN1LW monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP1304-Ag-1 | Recombinant multi-species OPSR/ OPN1LW/ CBBM protein |
ORF Viral Vector | vGMLP002980 | human OPN1LW Lentivirus particle |
ORF Viral Vector | pGMLP002980 | human OPN1LW Lentivirus plasmid |
Target information
Target ID | GM-IP1304 |
Target Name | OPN1LW |
Gene ID | 5956,699016,282293 |
Gene Symbol and Synonyms | CBBM,CBP,COD5,OPN1LW,OPSN,RCP,ROP |
Uniprot Accession | P04000,Q9BGI7 |
Uniprot Entry Name | OPSR_HUMAN,OPSR_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000102076 |
Target Classification | N/A |
The target: OPN1LW, gene name: OPN1LW, also named as CBBM, CBP, COD5, RCP, ROP. This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called red cone photopigment or long-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. This gene and the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of partial, protanopic colorblindness. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.