Anti-OPN1LW monoclonal antibody

Pre-made anti-OPN1LW monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to OPN1LW/OPN1LW products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP1304-Ab-1/ GM-Tg-hg-IP1304-Ab-2Anti-Human OPN1LW monoclonal antibodyHuman
GM-Tg-rg-IP1304-Ab-1/ GM-Tg-rg-IP1304-Ab-2Anti-Rat OPN1LW monoclonal antibodyRat
GM-Tg-mg-IP1304-Ab-1/ GM-Tg-mg-IP1304-Ab-2Anti-Mouse OPN1LW monoclonal antibodyMouse
GM-Tg-cynog-IP1304-Ab-1/ GM-Tg-cynog-IP1304-Ab-2Anti-Cynomolgus/ Rhesus macaque OPN1LW monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP1304-Ab-1/ GM-Tg-felg-IP1304-Ab-2Anti-Feline OPN1LW monoclonal antibodyFeline
GM-Tg-cang-IP1304-Ab-1/ GM-Tg-cang-IP1304-Ab-2Anti-Canine OPN1LW monoclonal antibodyCanine
GM-Tg-bovg-IP1304-Ab-1/ GM-Tg-bovg-IP1304-Ab-2Anti-Bovine OPN1LW monoclonal antibodyBovine
GM-Tg-equg-IP1304-Ab-1/ GM-Tg-equg-IP1304-Ab-2Anti-Equine OPN1LW monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP1304-Ab-1/ GM-Tg-hg-IP1304-Ab-2; GM-Tg-rg-IP1304-Ab-1/ GM-Tg-rg-IP1304-Ab-2;
GM-Tg-mg-IP1304-Ab-1/ GM-Tg-mg-IP1304-Ab-2; GM-Tg-cynog-IP1304-Ab-1/ GM-Tg-cynog-IP1304-Ab-2;
GM-Tg-felg-IP1304-Ab-1/ GM-Tg-felg-IP1304-Ab-2; GM-Tg-cang-IP1304-Ab-1/ GM-Tg-cang-IP1304-Ab-2;
GM-Tg-bovg-IP1304-Ab-1/ GM-Tg-bovg-IP1304-Ab-2; GM-Tg-equg-IP1304-Ab-1/ GM-Tg-equg-IP1304-Ab-2
Products NameAnti-OPN1LW monoclonal antibody
Formatmab
Target NameOPN1LW
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-OPN1LW monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP1304-Ag-1Recombinant multi-species OPSR/ OPN1LW/ CBBM protein
    ORF Viral VectorvGMLP002980human OPN1LW Lentivirus particle
    ORF Viral VectorpGMLP002980human OPN1LW Lentivirus plasmid


    Target information

    Target IDGM-IP1304
    Target NameOPN1LW
    Gene ID5956,699016,282293
    Gene Symbol and SynonymsCBBM,CBP,COD5,OPN1LW,OPSN,RCP,ROP
    Uniprot AccessionP04000,Q9BGI7
    Uniprot Entry NameOPSR_HUMAN,OPSR_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000102076
    Target ClassificationN/A

    The target: OPN1LW, gene name: OPN1LW, also named as CBBM, CBP, COD5, RCP, ROP. This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called red cone photopigment or long-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. This gene and the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of partial, protanopic colorblindness. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.