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Anti-SLC9A3R1 monoclonal antibody
Pre-made anti-SLC9A3R1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SLC9A3R1/SLC9A3R1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1747-Ab-1/ GM-Tg-hg-IP1747-Ab-2 | Anti-Human SLC9A3R1 monoclonal antibody | Human |
| GM-Tg-rg-IP1747-Ab-1/ GM-Tg-rg-IP1747-Ab-2 | Anti-Rat SLC9A3R1 monoclonal antibody | Rat |
| GM-Tg-mg-IP1747-Ab-1/ GM-Tg-mg-IP1747-Ab-2 | Anti-Mouse SLC9A3R1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1747-Ab-1/ GM-Tg-cynog-IP1747-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC9A3R1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1747-Ab-1/ GM-Tg-felg-IP1747-Ab-2 | Anti-Feline SLC9A3R1 monoclonal antibody | Feline |
| GM-Tg-cang-IP1747-Ab-1/ GM-Tg-cang-IP1747-Ab-2 | Anti-Canine SLC9A3R1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1747-Ab-1/ GM-Tg-bovg-IP1747-Ab-2 | Anti-Bovine SLC9A3R1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1747-Ab-1/ GM-Tg-equg-IP1747-Ab-2 | Anti-Equine SLC9A3R1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1747-Ab-1/ GM-Tg-hg-IP1747-Ab-2; GM-Tg-rg-IP1747-Ab-1/ GM-Tg-rg-IP1747-Ab-2; GM-Tg-mg-IP1747-Ab-1/ GM-Tg-mg-IP1747-Ab-2; GM-Tg-cynog-IP1747-Ab-1/ GM-Tg-cynog-IP1747-Ab-2; GM-Tg-felg-IP1747-Ab-1/ GM-Tg-felg-IP1747-Ab-2; GM-Tg-cang-IP1747-Ab-1/ GM-Tg-cang-IP1747-Ab-2; GM-Tg-bovg-IP1747-Ab-1/ GM-Tg-bovg-IP1747-Ab-2; GM-Tg-equg-IP1747-Ab-1/ GM-Tg-equg-IP1747-Ab-2 |
| Products Name | Anti-SLC9A3R1 monoclonal antibody |
| Format | mab |
| Target Name | SLC9A3R1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SLC9A3R1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1747-Ag-1 | Recombinant multi-species NHRF1/ SLC9A3R1/ EBP50 protein |
| ORF Viral Vector | pGMLP003586 | human SLC9A3R1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003586 | human SLC9A3R1 Lentivirus particle |
| ORF Viral Vector | pGMLV000651 | Norway rat Slc9a3r1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004928 | mouse Slc9a3r1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000651 | Norway rat Slc9a3r1 Lentivirus particle |
| ORF Viral Vector | vGMLPm004928 | mouse Slc9a3r1 Lentivirus particle |
Target information
| Target ID | GM-IP1747 |
| Target Name | SLC9A3R1 |
| Gene ID | 9368,26941,59114,703933,483299,101091236,505242,100052527 |
| Gene Symbol and Synonyms | EBP-50,EBP50,NHE-RF,NHERF,NHERF-1,NHERF1,NPHLOP2,SLC9A3R1 |
| Uniprot Accession | O14745,Q9JJ19,Q3SZK8 |
| Uniprot Entry Name | NHRF1_HUMAN,NHRF1_RAT,NHRF1_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000109062 |
| Target Classification | N/A |
The target: SLC9A3R1, gene name: SLC9A3R1, also named as EBP50, NHERF, NHERF-1, NHERF1, NPHLOP2. This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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