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Anti-SYP monoclonal antibody
Pre-made anti-SYP monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SYP/SYP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1872-Ab-1/ GM-Tg-hg-IP1872-Ab-2 | Anti-Human SYP monoclonal antibody | Human |
| GM-Tg-rg-IP1872-Ab-1/ GM-Tg-rg-IP1872-Ab-2 | Anti-Rat SYP monoclonal antibody | Rat |
| GM-Tg-mg-IP1872-Ab-1/ GM-Tg-mg-IP1872-Ab-2 | Anti-Mouse SYP monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1872-Ab-1/ GM-Tg-cynog-IP1872-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SYP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1872-Ab-1/ GM-Tg-felg-IP1872-Ab-2 | Anti-Feline SYP monoclonal antibody | Feline |
| GM-Tg-cang-IP1872-Ab-1/ GM-Tg-cang-IP1872-Ab-2 | Anti-Canine SYP monoclonal antibody | Canine |
| GM-Tg-bovg-IP1872-Ab-1/ GM-Tg-bovg-IP1872-Ab-2 | Anti-Bovine SYP monoclonal antibody | Bovine |
| GM-Tg-equg-IP1872-Ab-1/ GM-Tg-equg-IP1872-Ab-2 | Anti-Equine SYP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1872-Ab-1/ GM-Tg-hg-IP1872-Ab-2; GM-Tg-rg-IP1872-Ab-1/ GM-Tg-rg-IP1872-Ab-2; GM-Tg-mg-IP1872-Ab-1/ GM-Tg-mg-IP1872-Ab-2; GM-Tg-cynog-IP1872-Ab-1/ GM-Tg-cynog-IP1872-Ab-2; GM-Tg-felg-IP1872-Ab-1/ GM-Tg-felg-IP1872-Ab-2; GM-Tg-cang-IP1872-Ab-1/ GM-Tg-cang-IP1872-Ab-2; GM-Tg-bovg-IP1872-Ab-1/ GM-Tg-bovg-IP1872-Ab-2; GM-Tg-equg-IP1872-Ab-1/ GM-Tg-equg-IP1872-Ab-2 |
| Products Name | Anti-SYP monoclonal antibody |
| Format | mab |
| Target Name | SYP |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SYP monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1872-Ag-1 | Recombinant multi-species SYPH/ SYP/ MRX96 protein |
| ORF Viral Vector | vGMLP003530 | human SYP Lentivirus particle |
| ORF Viral Vector | pGMLP003530 | human SYP Lentivirus plasmid |
Target information
| Target ID | GM-IP1872 |
| Target Name | SYP |
| Gene ID | 6855,20977,24804,715739,612557,101084343,280937,100062804 |
| Gene Symbol and Synonyms | A230093K24Rik,MRX96,MRXSYP,p38,Syn,SYP,Syp1,XLID96 |
| Uniprot Accession | P08247,P07825,P20488 |
| Uniprot Entry Name | SYPH_HUMAN,SYPH_RAT,SYPH_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Desmoplastic small round cell tumor (DSRCT), Schizophrenia |
| Gene Ensembl | ENSG00000102003 |
| Target Classification | N/A |
The target: SYP, gene name: SYP, also named as MRX96, MRXSYP. This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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