Anti-™EM18 monoclonal antibody

Pre-made anti-™EM18 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™EM18/™EM18 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2021-Ab-1/ GM-Tg-hg-IP2021-Ab-2Anti-Human ™EM18 monoclonal antibodyHuman
GM-Tg-rg-IP2021-Ab-1/ GM-Tg-rg-IP2021-Ab-2Anti-Rat ™EM18 monoclonal antibodyRat
GM-Tg-mg-IP2021-Ab-1/ GM-Tg-mg-IP2021-Ab-2Anti-Mouse ™EM18 monoclonal antibodyMouse
GM-Tg-cynog-IP2021-Ab-1/ GM-Tg-cynog-IP2021-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM18 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2021-Ab-1/ GM-Tg-felg-IP2021-Ab-2Anti-Feline ™EM18 monoclonal antibodyFeline
GM-Tg-cang-IP2021-Ab-1/ GM-Tg-cang-IP2021-Ab-2Anti-Canine ™EM18 monoclonal antibodyCanine
GM-Tg-bovg-IP2021-Ab-1/ GM-Tg-bovg-IP2021-Ab-2Anti-Bovine ™EM18 monoclonal antibodyBovine
GM-Tg-equg-IP2021-Ab-1/ GM-Tg-equg-IP2021-Ab-2Anti-Equine ™EM18 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2021-Ab-1/ GM-Tg-hg-IP2021-Ab-2; GM-Tg-rg-IP2021-Ab-1/ GM-Tg-rg-IP2021-Ab-2;
GM-Tg-mg-IP2021-Ab-1/ GM-Tg-mg-IP2021-Ab-2; GM-Tg-cynog-IP2021-Ab-1/ GM-Tg-cynog-IP2021-Ab-2;
GM-Tg-felg-IP2021-Ab-1/ GM-Tg-felg-IP2021-Ab-2; GM-Tg-cang-IP2021-Ab-1/ GM-Tg-cang-IP2021-Ab-2;
GM-Tg-bovg-IP2021-Ab-1/ GM-Tg-bovg-IP2021-Ab-2; GM-Tg-equg-IP2021-Ab-1/ GM-Tg-equg-IP2021-Ab-2
Products NameAnti-™EM18 monoclonal antibody
Formatmab
Target Name™EM18
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™EM18 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2021-Ag-1Recombinant multi-species ™M18/ ™EM18/ lncND protein
    ORF Viral VectorpGMLP005040human ™EM18 Lentivirus plasmid
    ORF Viral VectorvGMLP005040human ™EM18 Lentivirus particle
    ORF Viral VectorpGMLPm003460mouse Tmem18 Lentivirus plasmid
    ORF Viral VectorvGMLPm003460mouse Tmem18 Lentivirus particle


    Target information

    Target IDGM-IP2021
    Target Name™EM18
    Gene ID129787,211986,362722,721515,607064,101092101,616554,100073041
    Gene Symbol and SynonymslncND,™EM18
    Uniprot AccessionQ96B42,Q6DGF8,Q3SZ36
    Uniprot Entry Name™M18_HUMAN,™M18_RAT,™M18_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000151353
    Target ClassificationN/A

    The target: ™EM18, gene name: ™EM18, also named as lncND. Predicted to enable DNA binding activity. Involved in cell migration. Located in nuclear membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.