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Anti-TSPAN32 monoclonal antibody
Pre-made anti-TSPAN32 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TSPAN32/TSPAN32 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2193-Ab-1/ GM-Tg-hg-IP2193-Ab-2 | Anti-Human TSPAN32 monoclonal antibody | Human |
| GM-Tg-rg-IP2193-Ab-1/ GM-Tg-rg-IP2193-Ab-2 | Anti-Rat TSPAN32 monoclonal antibody | Rat |
| GM-Tg-mg-IP2193-Ab-1/ GM-Tg-mg-IP2193-Ab-2 | Anti-Mouse TSPAN32 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2193-Ab-1/ GM-Tg-cynog-IP2193-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TSPAN32 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2193-Ab-1/ GM-Tg-felg-IP2193-Ab-2 | Anti-Feline TSPAN32 monoclonal antibody | Feline |
| GM-Tg-cang-IP2193-Ab-1/ GM-Tg-cang-IP2193-Ab-2 | Anti-Canine TSPAN32 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2193-Ab-1/ GM-Tg-bovg-IP2193-Ab-2 | Anti-Bovine TSPAN32 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2193-Ab-1/ GM-Tg-equg-IP2193-Ab-2 | Anti-Equine TSPAN32 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2193-Ab-1/ GM-Tg-hg-IP2193-Ab-2; GM-Tg-rg-IP2193-Ab-1/ GM-Tg-rg-IP2193-Ab-2; GM-Tg-mg-IP2193-Ab-1/ GM-Tg-mg-IP2193-Ab-2; GM-Tg-cynog-IP2193-Ab-1/ GM-Tg-cynog-IP2193-Ab-2; GM-Tg-felg-IP2193-Ab-1/ GM-Tg-felg-IP2193-Ab-2; GM-Tg-cang-IP2193-Ab-1/ GM-Tg-cang-IP2193-Ab-2; GM-Tg-bovg-IP2193-Ab-1/ GM-Tg-bovg-IP2193-Ab-2; GM-Tg-equg-IP2193-Ab-1/ GM-Tg-equg-IP2193-Ab-2 |
| Products Name | Anti-TSPAN32 monoclonal antibody |
| Format | mab |
| Target Name | TSPAN32 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TSPAN32 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2193-Ag-1 | Recombinant multi-species TSN32/ TSPAN32/ ART1 protein |
| ORF Viral Vector | pGMLP001216 | human TSPAN32 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001216 | human TSPAN32 Lentivirus particle |
Target information
| Target ID | GM-IP2193 |
| Target Name | TSPAN32 |
| Gene ID | 10077,27027,365390,704862,483667,101093396,530507,100630547 |
| Gene Symbol and Synonyms | Art-1,ART1,D7Wsu37e,PHEMX,PHMX,TSPAN32,TSSC6 |
| Uniprot Accession | Q96QS1 |
| Uniprot Entry Name | TSN32_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000064201 |
| Target Classification | N/A |
The target: TSPAN32, gene name: TSPAN32, also named as ART1, PHEMX, PHMX, TSSC6. This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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