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Anti-ARPC1A monoclonal antibody
Pre-made anti-ARPC1A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to ARPC1A/ARPC1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2360-Ab-1/ GM-Tg-hg-IP2360-Ab-2 | Anti-Human ARPC1A monoclonal antibody | Human |
| GM-Tg-rg-IP2360-Ab-1/ GM-Tg-rg-IP2360-Ab-2 | Anti-Rat ARPC1A monoclonal antibody | Rat |
| GM-Tg-mg-IP2360-Ab-1/ GM-Tg-mg-IP2360-Ab-2 | Anti-Mouse ARPC1A monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2360-Ab-1/ GM-Tg-cynog-IP2360-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ARPC1A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2360-Ab-1/ GM-Tg-felg-IP2360-Ab-2 | Anti-Feline ARPC1A monoclonal antibody | Feline |
| GM-Tg-cang-IP2360-Ab-1/ GM-Tg-cang-IP2360-Ab-2 | Anti-Canine ARPC1A monoclonal antibody | Canine |
| GM-Tg-bovg-IP2360-Ab-1/ GM-Tg-bovg-IP2360-Ab-2 | Anti-Bovine ARPC1A monoclonal antibody | Bovine |
| GM-Tg-equg-IP2360-Ab-1/ GM-Tg-equg-IP2360-Ab-2 | Anti-Equine ARPC1A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2360-Ab-1/ GM-Tg-hg-IP2360-Ab-2; GM-Tg-rg-IP2360-Ab-1/ GM-Tg-rg-IP2360-Ab-2; GM-Tg-mg-IP2360-Ab-1/ GM-Tg-mg-IP2360-Ab-2; GM-Tg-cynog-IP2360-Ab-1/ GM-Tg-cynog-IP2360-Ab-2; GM-Tg-felg-IP2360-Ab-1/ GM-Tg-felg-IP2360-Ab-2; GM-Tg-cang-IP2360-Ab-1/ GM-Tg-cang-IP2360-Ab-2; GM-Tg-bovg-IP2360-Ab-1/ GM-Tg-bovg-IP2360-Ab-2; GM-Tg-equg-IP2360-Ab-1/ GM-Tg-equg-IP2360-Ab-2 |
| Products Name | Anti-ARPC1A monoclonal antibody |
| Format | mab |
| Target Name | ARPC1A |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-ARPC1A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2360-Ag-1 | Recombinant multi-species ARC1A/ ARPC1A/ Arc40 protein |
| ORF Viral Vector | pGMLP002491 | human ARPC1A Lentivirus plasmid |
| ORF Viral Vector | vGMLP002491 | 0 ARPC1A Lentivirus particle |
| ORF Viral Vector | pGMLPm001975 | mouse Arpc1a Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001975 | mouse Arpc1a Lentivirus particle |
Target information
| Target ID | GM-IP2360 |
| Target Name | ARPC1A |
| Gene ID | 10552,56443,81824,718635,479745,101084410,508402,100059256 |
| Gene Symbol and Synonyms | 0610010H08Rik,1110030K07Rik,41kDa,Arc40,ARPC1A,HEL-68,HEL-S-307,Sid32,Sid329,SOP2Hs,SOP2L |
| Uniprot Accession | Q92747,Q99PD4,Q1JP79 |
| Uniprot Entry Name | ARC1A_HUMAN,ARC1A_RAT,ARC1A_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000241685 |
| Target Classification | N/A |
The target: ARPC1A, gene name: ARPC1A, also named as Arc40, HEL-68, HEL-S-307, SOP2Hs, SOP2L. This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
