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Anti-HOXD4 monoclonal antibody
Pre-made anti-HOXD4 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to HOXD4/HOXD4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2540-Ab-1/ GM-Tg-hg-IP2540-Ab-2 | Anti-Human HOXD4 monoclonal antibody | Human |
| GM-Tg-rg-IP2540-Ab-1/ GM-Tg-rg-IP2540-Ab-2 | Anti-Rat HOXD4 monoclonal antibody | Rat |
| GM-Tg-mg-IP2540-Ab-1/ GM-Tg-mg-IP2540-Ab-2 | Anti-Mouse HOXD4 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2540-Ab-1/ GM-Tg-cynog-IP2540-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HOXD4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2540-Ab-1/ GM-Tg-felg-IP2540-Ab-2 | Anti-Feline HOXD4 monoclonal antibody | Feline |
| GM-Tg-cang-IP2540-Ab-1/ GM-Tg-cang-IP2540-Ab-2 | Anti-Canine HOXD4 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2540-Ab-1/ GM-Tg-bovg-IP2540-Ab-2 | Anti-Bovine HOXD4 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2540-Ab-1/ GM-Tg-equg-IP2540-Ab-2 | Anti-Equine HOXD4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2540-Ab-1/ GM-Tg-hg-IP2540-Ab-2; GM-Tg-rg-IP2540-Ab-1/ GM-Tg-rg-IP2540-Ab-2; GM-Tg-mg-IP2540-Ab-1/ GM-Tg-mg-IP2540-Ab-2; GM-Tg-cynog-IP2540-Ab-1/ GM-Tg-cynog-IP2540-Ab-2; GM-Tg-felg-IP2540-Ab-1/ GM-Tg-felg-IP2540-Ab-2; GM-Tg-cang-IP2540-Ab-1/ GM-Tg-cang-IP2540-Ab-2; GM-Tg-bovg-IP2540-Ab-1/ GM-Tg-bovg-IP2540-Ab-2; GM-Tg-equg-IP2540-Ab-1/ GM-Tg-equg-IP2540-Ab-2 |
| Products Name | Anti-HOXD4 monoclonal antibody |
| Format | mab |
| Target Name | HOXD4 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-HOXD4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2540-Ag-1 | Recombinant multi-species HXD4/ HOXD4/ HHO.C13 protein |
| ORF Viral Vector | vGMLP004767 | human HOXD4 Lentivirus particle |
| ORF Viral Vector | pGMLP004767 | human HOXD4 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004552 | mouse Hoxd4 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004552 | mouse Hoxd4 Lentivirus particle |
Target information
| Target ID | GM-IP2540 |
| Target Name | HOXD4 |
| Gene ID | 3233,15436,288153,119867836,101098156,513306,102149632 |
| Gene Symbol and Synonyms | 6030436D05Rik,HHO.C13,Hox-4.2,HOX-5.1,HOX4,HOX4B,HOXD4 |
| Uniprot Accession | P09016 |
| Uniprot Entry Name | HXD4_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000170166 |
| Target Classification | N/A |
The target: HOXD4, gene name: HOXD4, also named as HHO.C13, HOX-5.1, HOX4, HOX4B, Hox-4.2. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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