Anti-CLCA4/ CaCC/ CaCC2 monoclonal antibody

Anti-CLCA4/ CaCC/ CaCC2 antibody for FACS & in-vivo assay

Target products collectionGo to CLCA4/CLCA4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0268-Ab-1/ GM-Tg-hg-MP0268-Ab-2Anti-Human CLCA4 monoclonal antibodyHuman
GM-Tg-rg-MP0268-Ab-1/ GM-Tg-rg-MP0268-Ab-2Anti-Rat CLCA4 monoclonal antibodyRat
GM-Tg-mg-MP0268-Ab-1/ GM-Tg-mg-MP0268-Ab-2Anti-Mouse CLCA4 monoclonal antibodyMouse
GM-Tg-cynog-MP0268-Ab-1/ GM-Tg-cynog-MP0268-Ab-2Anti-Cynomolgus/ Rhesus macaque CLCA4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0268-Ab-1/ GM-Tg-felg-MP0268-Ab-2Anti-Feline CLCA4 monoclonal antibodyFeline
GM-Tg-cang-MP0268-Ab-1/ GM-Tg-cang-MP0268-Ab-2Anti-Canine CLCA4 monoclonal antibodyCanine
GM-Tg-bovg-MP0268-Ab-1/ GM-Tg-bovg-MP0268-Ab-2Anti-Bovine CLCA4 monoclonal antibodyBovine
GM-Tg-equg-MP0268-Ab-1/ GM-Tg-equg-MP0268-Ab-2Anti-Equine CLCA4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0268-Ab-1/ GM-Tg-hg-MP0268-Ab-2; GM-Tg-rg-MP0268-Ab-1/ GM-Tg-rg-MP0268-Ab-2;
GM-Tg-mg-MP0268-Ab-1/ GM-Tg-mg-MP0268-Ab-2; GM-Tg-cynog-MP0268-Ab-1/ GM-Tg-cynog-MP0268-Ab-2;
GM-Tg-felg-MP0268-Ab-1/ GM-Tg-felg-MP0268-Ab-2; GM-Tg-cang-MP0268-Ab-1/ GM-Tg-cang-MP0268-Ab-2;
GM-Tg-bovg-MP0268-Ab-1/ GM-Tg-bovg-MP0268-Ab-2; GM-Tg-equg-MP0268-Ab-1/ GM-Tg-equg-MP0268-Ab-2
Products NameAnti-CLCA4 monoclonal antibody
Formatmab
Target NameCLCA4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CLCA4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CLCA4/ CaCC/ CaCC2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0268
    Target NameCLCA4
    Gene ID22802,362053,612508,101092951,507504
    Gene Symbol and SynonymsCaCC,CaCC2,CLCA4,Clca6,Prp3
    Uniprot AccessionQ14CN2
    Uniprot Entry NameCLCA4_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000016602
    Target ClassificationIon Channel

    The target: CLCA4, gene name: CLCA4, also named as CaCC, CaCC2. The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Alternative splicing results in multiple transcript variants, only one of which is thought to be protein coding. [provided by RefSeq, Dec 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.