Anti-CLC10/ CLEC10A/ CD301 monoclonal antibody

Anti-CLC10/ CLEC10A/ CD301 antibody for FACS & in-vivo assay

Target products collectionGo to CLEC10A/CLEC10A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0290-Ab-1/ GM-Tg-hg-MP0290-Ab-2Anti-Human CLEC10A monoclonal antibodyHuman
GM-Tg-rg-MP0290-Ab-1/ GM-Tg-rg-MP0290-Ab-2Anti-Rat CLEC10A monoclonal antibodyRat
GM-Tg-mg-MP0290-Ab-1/ GM-Tg-mg-MP0290-Ab-2Anti-Mouse CLEC10A monoclonal antibodyMouse
GM-Tg-cynog-MP0290-Ab-1/ GM-Tg-cynog-MP0290-Ab-2Anti-Cynomolgus/ Rhesus macaque CLEC10A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0290-Ab-1/ GM-Tg-felg-MP0290-Ab-2Anti-Feline CLEC10A monoclonal antibodyFeline
GM-Tg-cang-MP0290-Ab-1/ GM-Tg-cang-MP0290-Ab-2Anti-Canine CLEC10A monoclonal antibodyCanine
GM-Tg-bovg-MP0290-Ab-1/ GM-Tg-bovg-MP0290-Ab-2Anti-Bovine CLEC10A monoclonal antibodyBovine
GM-Tg-equg-MP0290-Ab-1/ GM-Tg-equg-MP0290-Ab-2Anti-Equine CLEC10A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0290-Ab-1/ GM-Tg-hg-MP0290-Ab-2; GM-Tg-rg-MP0290-Ab-1/ GM-Tg-rg-MP0290-Ab-2;
GM-Tg-mg-MP0290-Ab-1/ GM-Tg-mg-MP0290-Ab-2; GM-Tg-cynog-MP0290-Ab-1/ GM-Tg-cynog-MP0290-Ab-2;
GM-Tg-felg-MP0290-Ab-1/ GM-Tg-felg-MP0290-Ab-2; GM-Tg-cang-MP0290-Ab-1/ GM-Tg-cang-MP0290-Ab-2;
GM-Tg-bovg-MP0290-Ab-1/ GM-Tg-bovg-MP0290-Ab-2; GM-Tg-equg-MP0290-Ab-1/ GM-Tg-equg-MP0290-Ab-2
Products NameAnti-CLEC10A monoclonal antibody
Formatmab
Target NameCLEC10A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CLEC10A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CLC10/ CLEC10A/ CD301 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0290
    Target NameCLEC10A
    Gene ID10462,714099
    Gene Symbol and SynonymsCD301,CLEC10A,CLECSF13,CLECSF14,HML,HML2,MGL
    Uniprot AccessionQ8IUN9
    Uniprot Entry NameCLC10_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000132514
    Target ClassificationN/A

    The target: CLEC10A, gene name: CLEC10A, also named as CD301, CLECSF13, CLECSF14, HML, HML2, MGL. This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.